目的:研究针刺治疗更年期综合征的临床疗效及其内分泌机制.方法:47例更年期综合征患者分为针刺组32例(采用主穴肾俞、足三里、三阴交针刺治疗),对照组15例(采用口服谷维素治疗),观察两组治疗前后的Kupperman指数,进行疗效评价.并采用放射免疫分析法检测针刺组25例患者治疗前后血清E2、T、FSH、LH含量变化.结果:针刺治疗能改善更年期综合征患者的临床症状,疗效优于对照组;针刺治疗后患者血清E2含量明显升高,LH、T含量明显降低,FSH虽有下调趋势但无统计学意义.结论:针刺治疗更年期综合征疗效肯定.针刺治疗能够改善更年期综合征患者垂体-性腺轴的功能,该作用可能是其治疗更年期综合征的重要机制.
作者：马晓芃；吴富东；单秋华 刊期： 2009年第01期
目的:通过会阴超声显示的盆底肌肉运动、阴道内压力和盆底表面肌电的同步检测证实电针阴部神经刺激疗法确能兴奋阴部神经.方法:对骶部四个针刺点,采用长针(针灸针)深刺并加以电刺激直接兴奋阴部神经.在患者接受电针阴部神经刺激疗法的同时,使用带影像组件的Medtronic Duet Encompass尿动力仪同步显示会阴超声B模式下盆底肌肉运动和M模式下盆底肌运动曲线、阴道压变化曲线及盆底肌电波.同步检测亦在下列三种情况下进行:1)停止电刺激;2)减弱电刺激强度至原来的2/7左右;3)逐渐退出下两针使针尖离开原处1～2 cm.结果:35例女性压力性尿失禁患者(年龄54.9±9.8岁)接受了电针阴部神经刺激疗法和同步检测.当电针阴部神经刺激疗法正确实施时,患者有盆底肌以尿道为中心有节律地向头部方向收缩的感觉;同步检测显示超声B模式下盆底肌头尾方向运动,M模式下盆底肌运动曲线(振幅1 mm左右,n=31,14例≥1 mnl,17例＜1 mm),锯齿状阴道压变化曲线[变化幅度2.61±1.69(0.7～5.6)cmH2O2,n=34]和盆底肌电波[波幅23.9±25.3(5～96)μV,n=34].盆底肌运动曲线振幅大小与阴道压力变化幅度大小基本一致.当停止电刺激,减弱电刺激或针尖后退离开原处1～2厘米时,盆底肌运动及其运动曲线和锯齿状阴道压变化曲线消失.结论:电针阴部神经刺激疗法确能兴奋阴部神经,有效地收缩盆底肌.
作者：汪司右；颜娟娟；陈国美；徐名一 刊期： 2009年第01期
目的:观察项丛刺在治疗椎动脉型颈椎病中的作用.方法:将80例椎动脉型颈椎病患者随机分为项丛刺组和夹脊刺组,每组40例,项丛刺组采用项丛刺加颈夹脊刺,夹脊刺组单独采用颈夹脊刺,观察两组疗效及治疗前后椎动脉型颈椎病功能评定量表评分.结果:项丛刺组总有效率为95.0%,夹脊刺组总有效率为82.5%,经Ridit分析,u=5.186,P＜0.01,表明项丛刺组治疗椎动脉型颈椎病疗效优于夹脊刺组.项丛刺组椎动脉型颈椎病功能评定量表评分治疗前后差值和治疗后评分与夹脊刺组比较,差异均有统计学意义(P＜0.01),表明项丛刺组治疗对患者眩晕改善较夹脊刺组治疗更明显.结论:在颈夹脊刺基础上加项丛刺治疗椎动脉型颈椎病,能明显提高疗效.
作者：齐丽丽；杨玲 刊期： 2009年第01期
According to the concerned data from home and abroad,tobacco contains nicotine,coal-tar,CO and ammonia cyatic acid,and all of these chemical materials may damage some human organs.A large amount of statistic documents show that smoking does not only have close relationship with the onset of cancel but also affects the growth and development of fetus.Thus.a lot of people came for smoking cessation.During the recent years,some European and American countries have forbidden citizens to smoke in the public places.During the stay of the author in the medical team to Togo West Africa,80 foreign Patients were willing to receive acupunture treatment to stop smoking.The author found that it had a good effect to use ear acupoint with electroacupunture,the report is now as follows.
作者：居贤水 刊期： 2009年第01期
目的:探讨隔药饼灸抗衰老的临床疗效和免疫学机理.方法:采用隔药饼灸治疗223例老年人,观察隔药饼灸治疗前及治疗1疗程结束后衰老见症积分值,并检测血T淋巴细胞亚群、IL-2和β-内啡肽的变化.结果:223例老人经灸治后,衰老积分明显下降,在临床症状改善同时细胞免疫功能增强,T淋巴细胞总数增加,CD4+/CDs+比值恢复正常,IL-2合成分泌增加.β-EP作为免疫调节的神经介质,灸治后明显提高.结论:衰老过程与免疫功能密切相关.艾灸能纠正异常免疫状态、稳定机体内环境达到延缓衰老目的.
作者：赵粹英；杨玲；陈汉平；居贤水；吴恒举；丁菊英；施征；LI Sa；洪娴；张英英；王虹英 刊期： 2009年第01期
目的:观察头排针结合中药治疗帕金森病(Parkinson Disease,简称PD)的临床疗效.方法:150例PD患者按就诊先后随机分为4组,针药并用组(A组,88例)、针刺组(B组,20例)、中药组(C组,20例)和西药组(D组,22例).A组采用头排针结合滋补肝肾、活血祛风中药治疗,针刺隔日治疗1次,10次为1疗程;B组单纯使用头排针治疗,C组单纯使用滋补肝肾、活血祛风中药治疗,D组采用口服复方多巴胺药物治疗.4组均治疗1个治疗期(3个月)观察疗效.结果:A组总有效率为89.8%,与D组(86.4%)相比,无显著性差异(P＞0.05),但与C组(65.0%)相比,有显著性差异(P＜0.01).结论:针药并用治疗PD的疗效较好.
作者：黄文燕；奚桂芳；华雪桂 刊期： 2009年第01期
目的:观察针灸对克罗恩病大鼠血清TNF-a、sTNFR-Ⅰ、sTNFR-Ⅱ的影响.方法:采用TNBS制备大鼠克罗恩病模型,随机分为模型组、隔药灸组、电针组,并与正常大鼠作对照,采用HE染色观察结肠黏膜组织病理学变化,应用ELISA方法检测血清TNF-a、sTNFR-Ⅰ、sTNFR-Ⅱ的含量.结果:与正常组比较,CD大鼠血清YNF-a显著升高、sTNFR-Ⅰ和sTNR-Ⅱ无显著变化.经隔药灸和电针治疗后血清TNF-a水平显著降低,sTNFR-Ⅰ和sTNFR-Ⅱ无显著变化.CD大鼠结肠组织的炎症病变和异常的组织结构在隔药灸、电针治疗后得到明显改善.结论:隔药灸与电针均能够显著降低血清TNF-a的含量,该作用可能是隔药灸与电针治疗CD的作用机制之一.
作者：施征；马晓芃；吴焕淦；秦秀娣；钱晴兰；张卫 刊期： 2009年第01期
The Shanghai Journal of Acupuncture and Moxibustion and Journal of Acupuncture and Tuina Science wimessed a development of numerous authors.On the occasion of the 6th anniversary of Journal of Acupuncture and Tuina Science.I'd like to share my ideas about several issues on acupuncturemoxibustion science[1,2].
作者：陈汉文 刊期： 2009年第01期
Objective:To evaluate investigations of intestinal fibrosis of IBD treated by acupuncture and moxibustion and to analyze the current research situation of intestinal fibrosis.Methods:All reported studies were indexed about intestinal fibrosis of IBD treated by acupuncture and moxibustion and summarized the therapeutic effects of acupuncture and moxibustion on intestinal fibrosis.Results:Ten studies were included in this review,the research results indicated that acupuncture and moxibustion had beneficial effects not only on cytokines and colonic fibroblast but on collagen related to intestinal fibrosis.The expressions of TGF-beta and its mRNA were down regulated,and the expressions of IGF-1、IGF-1R and IGFBP-5 were decreased by acupuncture and moxibustion.The proliferative index of CBF was prohibited and the expression of type Ⅰ,Ⅲ,Ⅳ collagen was degraded by this therapy.Conclusion:Acupuncture and moxibustion can prevent and improve the colonic tissue fibrosis of IBD in some extent,but many research settings and methods should be improved to lucubrate the real therapeutic effects and the effective mechanism of acupuncture and moxibustion.
作者：王晓梅；丁光宏；刘慧荣；穆敬平 刊期： 2009年第01期
Objective:To observe the analgesia effect and of low-level combined- and single-laser irradiation on Zusanli (ST 36) in rats and the relationship between mast cell degranulation and laser acupuncture analgesia.Methods: A total of 66 Sprague Dawley (SD) rats were randomly assigned into normal control,model control,sham irradiation,10.6 μm laser (220 mW,40 Hz) 650nm laser(36mW,continuous),combined laser (10.6 μm+ 650 nm) groups.Arthritis mode 1 was established by injection of Complete Freund's Adjuvant (0.05 mL) into the left ankle joint.The paw withdrawal latency (PWL) was detected with a radiant heat algesimeter.Zusanli (ST 36) was irradiated with sham,single or combined laser for 30 min.After sacrifice under anesthesia (1% embutal),tissues of Zusanli (ST 36) area were sampled,sliced (5 μm) and stained with Toluidine Blue for skin for observing the mast cell degranulation.Results:Compared with model control and sham group,the pain threshold increased significantly in 650nm and combined laser groups (P＜0.01),while remained no significant difference in 10.6 μm group.Compared with model and sham group,the degranulation ratios of mast cells in 650nm and combined laser group were significantly higher (P＜0.001),while remained no significant difference in 10.6 μm group.The linear correlation coefficient between degranulation ratios of mast cells and PWL after laser acupuncture is 0.737 (P＜0.001).Conclusion:Both 650 nm and combined laser stimulation of Zusanli (ST 36) can effectively raise pain threshold,and enhance degranulation ratio of mast cells at the stimulated acupoint.The result also suggested a linear correlation between degranulation ratio of mast cell and analgesia effect.
作者：程珂；丁光宏；沈雪勇；吴凡 刊期： 2009年第01期
目的:观察电针预处理和电针治疗对缺血再灌注大鼠学习记忆功能的影响,为针灸参与中风后学习记忆功能障碍的早期防治和临床应用提供实验基础.方法:将72只清洁级雄性SD大鼠随机分为假手术组、模型组、术前电针组和术后电针组,通过观测各组大鼠避暗试验潜伏期和错误次数、神经功能缺损评分、患侧海马胆碱能受体结合量,分析术前和术后电针对脑缺血再灌注大鼠学习记忆功能的影响.结果:1)缺血后大鼠出现不同程度神经功能缺损体征.与假手术组相比,模型组神经功能缺损评分明显降低,避暗试验潜伏期和错误次数明显增加.mAchR的特异性结合量降低,与假手术组差异有显著性(P＜0.05).2)电针缺血大鼠可降低MCAO大鼠神经功能缺损积分,与模型组相比,术前电针组、术后电针组避暗试验潜伏期和错误次数,均有显著性差异(P＜0.05).3)与模型组比较,术前电针组mAchR结合量明显升高(P＜0.05),术后电针组mAchR结合量略有升高.结论:术前和术后电针均可延长避暗试验潜伏期,减少错误次数,而术前电针预处理可明显升高脑缺血再灌注所致异常降低的mAchR结合量,从而改善中枢胆碱能系统功能,改善学习记忆.提示电针预处理对预防缺血性脑血管病所致的学习记忆功能缺损有重要应用价值.
作者：葛林宝；方程；徐鸣曙；徐佳；李昌植 刊期： 2009年第01期
During bidding for the 973 national plan(leading development Proiect on basic studies),the authors made discussions and studies on moxibustion research and concluded that it is urgent to make preliminary explanation on its essential principle and application law.This article aims to review the urgency,key points and possibilities for breakthroughs in moxibustion study.
作者：吴焕淦；严洁；余曙光；马晓芃；刘慧荣 刊期： 2009年第01期
目的:探索针刺抗哮喘大鼠血清差异组份的研究方法.方法:用蛋白质SDS-PAGE技术,对针刺抗哮喘血清进行组份差异分析.结果:SDS-PAGE电泳显示了针刺与不针刺血清中差异蛋白的存在:1)与正常对照组相比,ADX Acup组血清组份Ⅰ和Asthma_Acup 组血清组份Ⅰ,均有一染色增高条带,其分子量为62.1kDa;2)与正常对照组相比,ADX Acup组血清组份Ⅲ有二条染色增高条带,其分子量分别为36.1kDa、12.3 kDa;3)与正常对照组相比,ADX Acup组血清组份Ⅲ有一条染色降低条带,其分子量为34.6kDa.提示针刺对血清蛋白具有上调和下调的双向调节作用.结论:针刺抗哮喘大鼠血清中存在不同的差异组份.针刺对血清蛋白具有上调和下调的双向调节作用.
作者：王宇；杨永清；马淑兰；崔建美；刘艳艳 刊期： 2009年第01期
Prof.HUANG Xian-ming(1920-),a famous acupuncturist at home and abroad,was appointed as the director of Shanghai Research Institute of Acupuncture and Meridian,director of WHO Shanghai International Acupuncture Training Center,chairman of shanghai Association of Acupuncture-moxibustion, vice president of China Association of Acupuncture and Moixbustion.
作者：黄葆华；吴焕淦；刘立公 刊期： 2009年第01期
YANG Yong-quan(1901-1981),a native of Nanhui county of Shanghai,studied with WANG Song-yu,a famous acupuncturist in Pudong area,at the age of seventeen.He returned to his hometown,Zhoupu town,to practice medicine,after he completed his study at the age of twenty.In 1937.
作者：杨依方；刘立公 刊期： 2009年第01期
运用计算机对130种古医籍中用针灸治疗阳痿的内容进行分析,总结古代医家针灸治疗本病的用穴规律.结果发现针灸治疗本病有循经取穴,分部取穴和辨证取穴特点.
作者：刘立公；顾杰 刊期： 2009年第01期
回顾1956～2007年针灸丈献,探索针灸治疗抑郁症用穴和治疗方法的规律.根据(《中国现代针灸信息数据库》数据,采用计量分析方法进行综合分析.结果提示百会、内关应用频次为,治疗方法以针刺为主.建议百会配内关作为针灸治疗抑郁症基础方,并随症选穴.
作者：黄琴峰 刊期： 2009年第01期
