杨绍安；刘宁富；舒小秋；肖晓桃
小儿麻痹造成股四头肌瘫痪,后遗膝关节屈曲挛缩,是小儿麻痹后遗症的常见病、多发病,常规矫正膝屈曲挛缩是小腿牵引加膝前沙袋加压,或月国窝软组织松解与肌腱延长,往往治疗效果不尽人意[1],甚至损伤神经血管.自行设计螺杆撑开器,矫正屈曲挛缩的膝关节,再行月国绳肌前移或缝匠肌止点不切断前移加强伸膝肌力[2-3],获得理想的治疗效果.
作者：陈秋生；杨建成；张颖；陈霞 刊期： 2002年第24期
股骨干骨折后牵引、整复、固定是治疗的基本原则,积极的功能训练也是确保治疗效果的重要因素.
作者：陈枢芹；张少臣 刊期： 2002年第24期
Many methods are adopted in treatment of osteoarthritis and NSAID drugs and hormones are often used in clinic,but these methods can only alleviate symptoms in a short time and can't prevent progressing of disease.Many researches have been done these years directing to the key that degeneration of cartilage and destroy of surface lead to osteoarthritis. Systematic clearance and douche under arthroscope have a good effect in alleviating pain and improving symptoms to osteoarthritis.
作者：王天胜；刘永灿；谢爱国；丁海蛟；滕寿发 刊期： 2002年第24期
Avulsion of scalp isn't rare in clinic and clinical data of 75 cases of avulsion of scalp from January,1958 to December,2001 is reviewed in this article to analyze relationship between avulsion type and late rehabilitation plastics , postoperative nursing instruction .
作者：刘云景；张琳西；戚锐 刊期： 2002年第24期
消化道测压是广泛使用的评价消化道功能的检查手段,对消化道运动障碍疾病的诊断有较高的价值,是其他检查手段不可替代的.文章从结肠压力信号中提取有效的特征,采用学习矢量量化的方法进行结肠压力信号的识别.学习结果表明,这种方法可以将结肠压力信号分为正常与异常两组,与初始的医疗诊断相符合.这一研究为进一步根据结肠压力信号识别肠道各段的动力性能奠定了基础.
作者：颜国正；迟冬祥；王文兴；林良明；张根福；史熠；宋安 刊期： 2002年第24期
腰椎间盘突出症是为常见的一种腰腿痛[1].为探索简便易行,治愈率高的非手术疗法,自1996年以来,我们采用口服药酒配合推拿治疗腰椎间盘突出症患者116例,取得了良好的效果,现报告如下.
作者：乔国一；王强；邵宗军 刊期： 2002年第24期
Background:Fracture of calcaneus often leads to pain,deformity,function of foot is impaired and even permanent function impairments are left.Many divergence existed in treatment of severe intra articular fracture existed,but with the development of pedal surgery and deep study of biomechanics anatomy,especially building of BO theory,the therapeutic programs have become clearer.
作者：金晨；胡小鹏；杨裕红；张德常；陈学桂；吴揭地 刊期： 2002年第24期
Background:For the clinical treatment of dislocation of distal radioulnar articulation, removal of smaller head of ulna was often adopted .Because this operation damaged ulnar stabilization of wrist, therapeutic effect couldn't be sustained for a long time, even semiluxation of carpal bone appeared.
作者：范少地；钟桂舞；闫自强 刊期： 2002年第24期
This article summarized exposure area, treatment of mental nerve, soft tissue stalk, osteotomy position and fixation method. 1 Mental part exposure area and treatment of mental nerve.
作者：刘妍琼；华泽权 刊期： 2002年第24期
Background: The effects that total hip replacement (THR) can alleviate pain, reconstruct function of hip joint and improve patients' daily living ability have been proved, success has a direct relationship with postoperative function exercises.
作者：靳徐凤 刊期： 2002年第24期
目的采研究少儿与成年人大面积重度烧伤后瘢痕组织表皮干细胞分布与表达β1整合素和角蛋白19,14,10(K19,K14,K10)的特征与规律.方法分别取4～12岁少儿及35～53岁成年人2组健康皮肤及大面积深度烧伤后瘢痕组织.采用免疫组织化学SP法检测表皮干细胞、短暂扩充细胞特异表达的β1整合素和K19以及分化表皮细胞表达的K14和K10.结果瘢痕组织表皮基底层表达β1整合素与K19的阳性细胞数较健康皮肤明显减少,阳性强度降低.瘢痕组织表皮中表达K14的阳性细胞仅位于表皮底部二三层,明显少于健康皮肤,而K10表达阳性细胞则较健康皮肤分布广泛.结论瘢痕组织表皮的增殖能力下降,细胞的分化行为紊乱,这可能是瘢痕组织表皮结构与功能改变、愈合能力下降的原因之一.
作者：赵志力；付小兵；孙同柱；杨银辉；陈伟；孙晓庆；盛志勇 刊期： 2002年第24期
目的探讨大连市乳腺癌患者放疗期间人格与生存质量的相关性.方法采用已经过检验的美国希望城(hopecity)医学研究中心编制的<乳腺癌患者生活质量评定量表>和艾森克人格量表(EPQ).于2001年3～12月对正在大连市综合医院和肿瘤专科医院放射治疗的71例女性乳腺癌根治术后的患者进行问卷调查.统计学方法采用单因素相关分析.结果乳腺癌患者在放疗前、中、后人格分值与生存质量分值呈正相关.在放疗前、中、后人格的N因子与生存质量的躯体、心理、社会因子呈正相关;放疗前、中P因子与生存质量的精神因子呈正相关,放疗后与躯体因子呈正相关;L因子在放疗前、后与精神因子呈负相关.结论乳腺癌患者人格与生存质量之间存在密切的关系,而相关的主要因素是N因子(神经质),其次是P因子(精神质)和L因子(掩饰);与E因子(内外向)无关.
作者：王若雨；姜潮；刘启贵；孙月吉；李玉民；谭淑媛 刊期： 2002年第24期
目的探讨椎动脉型颈椎病的发病机制及中药止眩灵对大鼠离动脉的舒张作用及血液流变学的影响.方法取SD大鼠50随机分为高浓度组、中浓度组、低浓度组西比灵对照组.空白组各式10只,观察其血液流血的改变情况;取雄性大鼠20只开胸取主动脉制成长约3～5mm的胸主动脉环,加入不同能浓度的止眩灵观察其舒张作用.结果不同浓度的止眩灵对大鼠离动脉均有不同程的舒张作用及血液流变学的改变.高浓度组与空白的对照组差异有显著性意义(P<0.01),并受一氧化氮释放浓度的影响.结论止眩灵具有舒张血管的作用.影响血液流度学的改变,但与一氧化氮的释放浓度有关.
作者：梁必如；苏培基；吴俊哲；黄世波；潘乘龙 刊期： 2002年第24期
截肢后安装假肢是重建肢体功能的重要手段,及时正确的康复训练有助于充分发挥假肢的代偿作用,让患者尽早回归社会.文章就截肢康复的重要性、我国截肢康复的现状、现代截肢康复的特点及主要方法等作一综述.
作者：杨东运 刊期： 2002年第24期
Background:The senlie with fracture rest in bed for a long time,and haven't sufficient function exercise,all above will lead to osteoporosis,bad repair of bone tissue,muscle atrophy and joint stiffness occurs,which bring suffering and enconomic burden.
作者：王传铭；王莹 刊期： 2002年第24期
Objective To study the changes and significance of neuron specific enolase(NSE) and glial fibrilous acidic protein(GFAP) in rat cerebral concussion.Methods 80 Wistar male rats were used for animal model of cerebral concussion,which were sacrificed on the 1st,3rd, 7th,14th and 30th days after injury and the brain tissue were taken off.The expressions of NSE and GFAP were studied in the course of cerebral concussion by means of immunohistochemistry. Results Rats in 100 g group were seen the clinical manifestation for typical concussion.The pathologic changes were the cerebral vascular constriction and dilation,congestion and edema of cerebral tissue and neuronal degeneration and necrosis.NSE was increased on the 1st day,and the positive area was seen in the plasma of the neurons in the cerebral cortex and the cerebellum,and also seen in blood vessels,cerebrospinal fluid in aqueduct and interstitial matrix.NSE was obtained at peak on the 7th day,decreased on the 14th day and still raised on the 30th day.GFAP was increased on the 1st day,which the positive area was seen in the plasma of astrocytes,and obtained at peak on the 3rd day,which fiber like GFAP was in short,thick and astrocytes increased.GFAP decreased on the 7th day and obtained normal level in 30 days.Conclusion The main pathologic changes of cerebral concussion were blood circulatory disorder and nervous cells degeneration,apoptosis and necrosis.NSE and GFAP participated in the course of cerebral concussion,may play an important role in the damage of blood brain barrier, nervous cells degeneration and necrosis.
作者：彭瑞云；高亚兵；王德文；肖兴义；陈浩宇；吴小红；刘杰；胡文华；蔡宝仁；薛官生；张援平；尹晓梅 刊期： 2002年第24期
在腰椎间盘突出症非手术治疗方法中,硬膜外腔注射药物是一种有效快捷的治疗方法.常规的方法是经后正中入路将药物注入硬膜外后腔,近2年来运用改良入路将药物直接注入侧隐窝治疗该病,报道如下.
作者：车润平；庞秀丽；王娟；张平 刊期： 2002年第24期
氟西汀是临床上常用的选择性5-羟色胺重摄取抑制剂,用于抗抑郁症的治疗.氟西汀在肝脏由细胞色素P450酶进行氧化代谢.现已知N-去甲基代谢是主要代谢途径,其次为O-脱烷基代谢.文内所述的体内和体外研究表明,CYP2C19和CYP2C9是催化氟西汀N-去甲基代谢的主要CYP酶,而CYP2C19和CYP3A4是催化O-脱烷基代谢的主要CYP酶;多态性CYP2C19对氟西汀代谢的作用均呈底物剂量依赖性和基因剂量效应.这些研究结果将为临床上合理使用氟西汀提供重要的实验依据.
作者：刘昭前；莫玮；王丹；周宏灏 刊期： 2002年第24期
目的探讨颅内电极监测癫痫发作初始期脑电对致痫灶的定位价值.方法14例难治性癫痫患者,其临床、影像学检查及头皮脑电记录等不能精确定位致痫灶,经颅骨钻孔、埋置颅内深部和/或皮层电极,长程脑电监测并分析发作初始期脑电的异常放电节律和范围,对比术后病理学检查和随访结果,分析发作初期脑电定位致痫灶的准确性.结果记录到了47次临床发作.发作初期异常放电可分为4种形式:低幅快节律、尖波节律、高幅棘波节律和棘慢波节律.按异常放电范围可分为:局限性放电、区域性放电和广泛性放电.11例(78.5%)患者准确定位了致痫灶,术后癫痫发作消失(64.3%)或极少发作(14.2%),2例(14.2%)发作减少90%以上,1例(7.1%)术后无改善.结论颅内埋置电极脑电监测癫痫发作初始期异常放电形式、部位和异常放电范围是定位致痫灶可靠的方法.
作者：张国君；王玉平；遇涛；李勇杰 刊期： 2002年第24期
Background:Traction of cervical vertebrae is an effective method in treatment of cervical spondylopathy. Manual therapy can correct dysfunction,has the effects of function exercises and has an active significance to the rehabilitation of mixed cervical spondylopathy.Combination of these two methods could enhance therapeutic effects and do good to functional recovery.
作者：李兴海；李丹 刊期： 2002年第24期
中国组织工程研究杂志
主管:中华人民共和国卫生部
主办：中国康复医学会,《中国组织工程研究与临床康复》杂志社
