原毅；李颖；柳莹；尹健
BACKGROUND:The direction of modern research on rehabilitation is to recover the function,and improve patients' motion,living ability,make them turn round to family and society.
作者：谢淑丽；朱明光；张小丽 刊期： 2003年第01期
由于慢性肝炎具有持续存在、反复发作及传染性等特点,慢性肝炎患者容易由疾病的挫折和冲突引起长期焦虑而出现以神经症为主要形式的心理障碍,表现为神经衰弱、焦虑神经症及恐怖症等.当慢性肝炎患者出现心理障碍时,一方面严重影响肝脏疾病的治疗与康复,另一方面可诱发心身疾病.因此,对慢性肝炎心理障碍患者进行心理治疗具有非常重要的意义.作者用个体心理疗法或行为疗法等对一些典型的慢性肝炎心理障碍患者,进行心理治疗,取得满意疗效.
作者：李跃旗；孙惠莉；石建时；李琳；赵蕊 刊期： 2003年第01期
BACKGROUND:Electrocardiogram(ECG) reaction of patients with coronary heart disease(CHD) are not improved markedly by medical therapy,but the patients' S T,T of ECG are improved obviously by HBO therapy.
作者：王超英；王杰；孙海玲 刊期： 2003年第01期
针对高能聚焦超声在肿瘤治疗的应用过程中要解决的关键问题-成像、定位和聚焦及对关键问题常用的解决方法进行了简介,在进行比较的基础上选定了成像和聚焦解决方法;并在此基础上提出了一种高能聚焦超声肿瘤治疗仪的实现方案,对超声肿瘤治疗仪的关键部件治疗头部和臂部的结构结合实现功能进行了分析.分析了高能聚焦超声肿瘤治疗仪进行肿瘤治疗的过程:术前规划和手术模拟、术中定位和跟踪和术后治疗效果的评价.
作者：项林清；马培荪；陈亚珠；潘刚 刊期： 2003年第01期
目的:通过2型糖尿病患者与正常对照者之间的比较,分析血清瘦素与多种影响因素的关系.方法:对样本人群进行流行病学问卷调查、体检并测定了血糖、血脂、胰岛素和血清瘦素等生化指标,通过病例对照研究方法加以分析.结果:2型糖尿病患者血清瘦素为(9.43±6.15)ng/ml,正常对照为(9.48±5.60)ng/ml.无论有无糖尿病肥胖者血清瘦素约是非肥胖者的2倍,女性约是男性的3倍.结论:2型糖尿病患者与正常对照者间的血清瘦素不存在显著性差异,可能与患者坚持治疗病情控制良好有关.血清瘦素受到吸烟、性别、体脂、血脂和饮食等多方面因素的共同影响,高密度脂蛋白胆固醇可能是其保护因素.
作者：谢娟；郭刚；来则民；张镜宇；木村美惠子 刊期： 2003年第01期
目的:探讨应用姑息治疗对提高晚期癌症患者生活质量 (quality of life, QOL)的影响.方法:对 96例晚期癌症患者进行姑息治疗,采用 QOL观察指标对本组病例治疗前、后评分,将 QOL分为好≥ 41分;中 21～40分;差≤ 20分共 3个等级进行评估.结果:本组病例 QOL评分,治疗前≤ 40分、治疗后≥ 41分者为 71例;治疗前≤ 20分、治疗后≥ 21分者为 12例;治疗前后无效者 13例. QOL提高者占 86%,无效为 14%.结论:姑息治疗能提高晚期癌症患者的 QOL.
作者：赵勤 刊期： 2003年第01期
0 引言经颅多普勒( TCD)借助脉冲多普勒技术和 2 MHz频率超声波,经特定颅骨透声窗,直接描记脑血管多普勒信号,以获取脑动脉血流动力学参数,进而反应脑血管功能状态.
作者：李秀珍；史洪润；张国忠；姚勇；李新民；殷宇刚；韩恩吉 刊期： 2003年第01期
目的:探讨氟西汀抗抑郁治疗对卒中后抑郁( Post Stroke Depression, PSD)患者神经功能康复的影响.方法:选取经临床体格检查、头颅 CT或 MRI确诊的急性脑卒中患者 132例(脑梗死 78例,脑出血 54例).将符合 DSM Ⅳ抑郁症诊断标准的脑卒中患者随机分成抑郁治疗组和抑郁对照组,治疗组予氟西汀治疗.分别在病程 2周、1月、3月、6月、12月时给每一位入组患者行神经功能缺损评分( SSS)、日常生活能力评分( ADL)、汉密尔顿抑郁量表( HAMD)、 Zung's抑郁自评量表( SDS)和焦虑自评量表( SAS)评分.结果:脑卒中患者中约 44.7%出现抑郁症状;抗抑郁药物 PROZAC(盐酸氟西汀)能明显改善病程 3, 6月时神经功能缺损,病程 12月时不仅抑郁症状减轻, ADL能力改善,神经功能缺损减轻尤为显著.结论:抗抑郁治疗能使 PSD患者抑郁症状明显改善的同时,显著提高 ADL能力和神经功能.
作者：程丰；邵国富；包仕尧 刊期： 2003年第01期
AIM:To explore the membrane permeability, enzyme tolerance, and stability of phosphorothioate oligodeoxynucleotide(P ODN) which can inhibit cerebral thrombosis.METHODS:(1)Oligodeoxynucleotide was synthesized with phosphoramidite method in solid phase,3' end was modified with thiophosphoter.(2)Uptake and subcellular distribution of P ODN.P ODN was given directly.We observed total uptake rate of P ODN by ECV304 cells and subcellular distribution of P ODN.RESULTS:(1)ECV cells uptake more P ODN with increase of concentration,the uptake rate was about 10.8% - 11.9% .(2)Subcellular distribution of P ODN:P ODN was mainly distributed in nucleus especially nucleus sediments(69.3% - 77.2% )(P< 0.05).CONCLUSION:P ODN suppressing cerebral thrombosis has favorable transmembrane ability,enzyme resistance and stability.
作者：李黔宁；应大君；戴光明；郑健；王东武；肖道虹；刘勇；邓志宽；刘立杰；周永琴 刊期： 2003年第01期
0 引言对阿尔茨海默病 (Alzheimer disease,AD)以上市的安理申和石杉碱甲 (商品名哈伯因,军事医学科学院研制、河南从生制药厂出品 )应用较为广泛.石杉碱甲治疗 AD的效果,文章对此作了报道.
作者：宋志宇；卢宏 刊期： 2003年第01期
BACKGROUND:The therapy of seawater bath can make the speed of fat oxidation by body tissue and liver faster and has a better curative effect on the patients with hyperlipemia and hypertension.Hyperlipemia do harm to severely the health of middle aged and elders and can cause hypertension and coronary heart disease.The treatment of sea bath can make 80% cholesterol become cholic acid in liver and at last bile salt,which is drained with bile to intestines.HDL C is demomposed with the consumption of TC and TG,which showes the trendency of gradually in creasing in content and helps cleaning fat rubbish.
作者：沈淑花 刊期： 2003年第01期
AIM:To evaluate the effectiveness of hospitalized occupational rehabilitation for chronic schizophrenic patients in social functioning.METHODS:79 qualified cases were selected from chronic psychiatric inpatient departments,divided into two groups randomly,of which 45 cases of treatment group accepted hospitalized occupational rehabilitation,another 34 cases of control group accepted ordinary treatment.Social functioning was evaluated by the Scale of Social Skills of Chronic Schizophrenic In patients(SSSI). RESULTS:6 month course of research figured out that the rank of improvement of the total disability degree of the treatment was significantly larger than that of the control group(P< 0.05).Items of which rank of improvement of the treatment was significantly larger than those of the control group are participating in the occupational rehabilitation,social withdraw and concern and care about others (P< 0.01- 0.05).The level of disability of 55.6% of the treatment decreased more than that of the control (26.5% ) (P< 0.05) evaluated by SSSI.CONCLUSION:Hospitalized occupational rehabilitation is effective in improving social functioning of chronic schizophrenic patients,especially in improving items like participating in the occupational rehabilitation, social withdraw and concern and care about others.
作者：卢苓；马胜民；翁永振；崔仁祥 刊期： 2003年第01期
0 引言失眠不但加重原有的精神疾病,而且影响患者的工作和学习效率,特别是与记忆,计算和逻辑推理有关的精神活动,情绪沮丧、焦躁,进而影响人际关系.
作者：张淑兰；安俊峰；林桂梅；李银霞 刊期： 2003年第01期
0 引言对昆明市儿童医院新生儿科 2000 01/2001 05出院的 200例高危新生儿进行了监测,并对筛查出的脑性瘫痪 (脑瘫 )患儿进行分析总结.
作者：刘芸；李丽君；唐学兵 刊期： 2003年第01期
BACKGROUND:Ischemic preconditioning occur refers to the occurrence of many unstable angina pectoris before acute myocardial ischemia(AMI).It is generally recognized that ischemic preconditioning occur has protective effect on heart and can reduce infarction scope and improve contraction function of heart.Recently some authors thinks ischemic preconditioning occur will cause the exacerbation of patients' condition during the time of hospitalization and increase the incidence rate of angina and pectoris and death.
作者：王若楠；王兵 刊期： 2003年第01期
BACKGROUND:Cervical vertigo(CV) belongs to vertebral artery type of cervical spondylopathy which clinical manifestation was paroxysmal vertigo and is highly related to cervical motion.Recent clinical experiences proved that comprehensive treatment was superior to simple treatment.Because of patients were in different departments,therapeutic methods were also different,effects produce slowly,remote effects were not obvious and recurrence rate was higher.
作者：曾西；陈尚康；关晨霞；彭予忠；姜丽 刊期： 2003年第01期
INTRODCTIONIncidence of osteoporosis is very high in menopausal women and the senile.There weren't satisfying therapeutic method at present and exercises,diet,shinning,drugs were the main basic treatment for osteoporosis which preventive effects were better than therapeutic effects.Scientific exercises plus diet containing high calcium or suitable supplement of calcium is an effective preventive method for osteoporosis.
作者：单述刚；段献荣 刊期： 2003年第01期
目的:观察垂体腺苷环化酶激活肽(pituitaryadenylatecyclaseactivatingpolypeptide,PACAP)对缺血再灌注脑神经元凋亡的防治作用.方法:利用四血管结扎法,建立老龄大鼠脑缺血再灌注模型,侧脑室注射PACAP,观察脑组织丙二醛(MDA)含量和超氧化物歧物酶(SOD)、谷胱甘肽过氧化物酶(GSHPx)活性,计数海马CA1区存活和凋亡神经元数目,电镜观察神经元的超微结构变化.结果:PACAP治疗后脑组织MDA含量为(1.35±0.39)nmol/mg,SOD和GSHPx活性分别为(115±20)NU/mg、(10.3±2.0)U/mg,与缺血再灌注组有明显差异(P<0.05),海马CA1区存活和凋亡神经元数目为48.8±4.3,14.3±2.9,能促进神经元存活和减轻凋亡损伤(P<0.01),保护超微结构.结论:PACAP的保护作用可能与其降低脑组织氧自由基水平,提高抗氧化酶活性,防止神经元凋亡有关.
作者：刘宪霜；崔旭；王鲁宁；李文彬；韩志涛；尹志奎；房征宇 刊期： 2003年第01期
0 引言新生儿缺氧缺血性脑病(HIE)是指在围产期窒息导致脑的缺氧缺血性损伤.
作者：陈虹；王倩；黄瑞兰 刊期： 2003年第01期
INTRODUCTIONMassage has become a manipulation of physical therapy in recent years.Massage is based on theory of zang and fu, channel and collateral of traditional Chinese medicine,instructed by pathology,anatomy and diagnosis of western medicine and combined with kinds of massage manipulation all which have make it an important method of nondrug therapy in preventing and treatment of diseases.Massage is also a measure in rehabilitation of motion function of patients with stroke[1].
作者：李晓榕；杨海玲；聂怀利 刊期： 2003年第01期
中国组织工程研究杂志
主管:中华人民共和国卫生部
主办：中国康复医学会,《中国组织工程研究与临床康复》杂志社
