Purpose:To evaluate the efficacy and safety of using coreoplasty,and an iris-supported Artisan intraocular lens (IOL),for mydriasis and aphakic correction in post-traumatic vitrectomized eyes.Methods:A total of 17 aphakic patients were admitted between April 2009 and April 2010 to the ophthalmologic department of Xiamen Eye Centre.All eyes had previously received lens removal and vitrectomy.After the retina stabilized and corrected visual acuity improved,the iris was sutured.The Artisan IOL was fixated onto the iris surface.Patients were followed-up at one day,one week,one month and three months postoperatively.The following outcomes were assessed:symptoms of photophobia and glare,uncorrected visual acuity (UCVA),best-corrected visual acuity (BCVA),intraocular pressure (IOP),endothelial cell density (ECD).The diameter of pupil and the anterior chamber depth (ACD)were measured by the anterior segment optical coherence tomography (OCT).Results:Artisan IOLs were successfully implanted in all aphakic eyes.Postoperatively,improvement was observed in photophobia and glare symptoms.UCVA was enhanced in all patients (six eyes had better UCVA postoperatively than BCVA preoperatively).However,there were no significant changes in IOP.Mean loss of ECD was 336.06/mm2.Mean postoperative pupil diameter was 3.67±0.41 mm,compared with 5.67±0.57 mm preoperatively(P＜0.05).Mean ACD was reduced by 0.88 mm (3.38±0.33 mm preoperatively vs 2.50±0.35 mm postoperatively,P＜0.05).Conclusion:Surgery that combined coreoplasty and Artisan IOL implantation was a safe and effective treatment for correcting aphakia and mydriasis in post-traumatic vitrectomized eyes.

作者：Haibo Li；Jinhong Cai；Yanming Huang；Duanxiao Wu；Yue Zhang；Donghai Wu 刊期： 2012年第03期

Purpose:To investigate the efficacy of progressive addition lenses on the treatment of ametropia and loss of accomodation after the single eye's IOL implantation.Methods:Eighty four patients undergoing IOL implantation in single eyes were prescribed with progressive addition lenses for ametropia correction and regularly followed up to observe subsequent correction effect.Results:Among these 84 patients,72 could comfortably adapt to the use of progressive addition lenses to improve visual acuity and accomondation,while the remaining 12 patients failed to accomodate the usage of progressive addition lenses.Conclusion:Wearing progressive addition lenses acts as a relatively feasible approach to improve visual acuity and alleviate disorders of accomodation for patients who underwent IOL implantation in single eyes.The patients should be prescribed with progressive lenses under professional instructions and guidance.

作者：Linxing Chen；Yingyu Zeng；Junwen Zeng；Mingguang He 刊期： 2012年第03期

Purpose:To report on the clinical findings of a case of late opacification of the hydrophobic acrylic intraocular lens (IOLs) in both eyes after cataract surgery.Methods:A 79-year-old man with a history of decreased visual acuity and complaints of glare and blurred vision in both eyes over the past 3 years.He had received an uneventful phacoemulsification combined with posterior chamber IOL implantation for senile cataract in both eyes 13 years ago,and had undergone neodymium:YAG (Nd:YAG) laser posterior capsulotomy on both eyes 6 years ago,for posterior capsular opacification (PCO).The optical portion of the IOLs showed uniform gray haze.Binocular posterior capsular laser holes were clearly noted.Results:IOL exchange was performed by the same surgeon on both eyes,three days apart.Postoperatively,the patient's visual acuity was elevated to 6/12 (OD) and 6/9 (OS) at 6months,and intraocular pressure (IOP) reached 16.8 mmHg (OD) and 18.4 mmHg (OS).Neither glare or blurred vision were observed in either eye.Conclusion:IOL exchange can be used to effectively manage clinically significant optic opacification.

作者：Shengli Hao；Hong Zhang 刊期： 2012年第03期

Purpose:To compare melanin-related near-infrared fundus autofluorescence (NIA; excitation 787 nm,emission＞ 800 nm)with lipofuscin-related fundus autofluorescence (FAF; excitation 488 nm,emission ＞ 500 nm) in patients with idiopathic choroidal neovascularization (ICNV).Methods:FAF,NIA,fundus fluorescein angiography (FFA)and indocyanine green angiography (ICGA) were obtained using a confocal scanning laser Ophthalmoscope HRA2 (Heidelberg Retina Angiograph 2) in 18 eyes of 18 patients with ICNV.Results:Eighteen eyes had classic CNV,and autofluorescence imaging showed hypoautofluorescence at the site of CNV.A well-defined hyperautofluorescent ring was detected surrounding the CNV in all 18 eyes with NIA imaging.In our sample,the FAF patterns around the CNV were classified as normal (n=1,5.56％),well-defined hyperautofluorescent ring (n=7,38.89％),or ill-defined hyperautofluorescent ring (n=10,55.56％).Conclusion:The patterns of FAF and NIA indicated different involvement of lipofuscin and melanin in the pathophysiological process of ICNV.Compared to FAF imaging,NIA imaging appears to be a superior noninvasive method for in vivo visualization of retinal pigment epithelium (RPE) abnormalities in ICNV patients.

作者：Xijia Peng；Wenfang Zhang 刊期： 2012年第03期

Purpose:To assess the efficacy of vitrectomy combined with intravitreal injection in the treatment of endophthalmitis after phacoemulsification and IOL implantation.Methods:Five patients (5 eyes),who had undergone conventional phacoemulsification combined with IOL implantation at another treatment facility,presented with endophthalmitis.The subjects ranged in age from 41 to 79 years (65.8±0.5years on average),and three were male.All five cases received bacterial culture susceptibility testing.On the basis of the treatment of primary disease,3 cases had anterior chamber irrigation,and posterior vitrectomy followed by intravitreal injection of 1 mg vancomycin plus 2.25 mg ceftazidime.Results:Four out of the five cases of endophthalmitis had a positive bacterial culture testing results (two cases of staphylococcus epidermidis,one case of enterococcus faecalis and one case of head-like staphylococcus),and the remaining case had no bacterial growth.Four cases showed restored visual acuity,clear vitreous cavity,and no retinal detachment or other complications.Conclusion:Management of patients presenting with endophthalmitis subsequent to cataract surgery should include:prompt bacterial culture and drug sensitivity tests,and where appropriate,vitrectomy combined with intravitreal injection of vancomycin.

作者：Jing Zhu；Yuli Pi；Qing Guo；Zhaohui Li 刊期： 2012年第03期

Purpose:To study the effect of intravitreal injections of triamcinolone acetonide (TA) for the treatment of macular edema secondary to central retinal vein occlusion (CRVO)in a sample of Chinese patients from Shaanxi province.Methods:The 50 eyes from 50 patients were separated into three TA treatment groups:17 patients were given 4 mg/0.1ml,19 patients were given 8 mg/0.2 ml,and 14 patients were given 16 mg/0.4 ml.Patients were followed up for 12 months.Foveal thickness,intraocular pressure (IOP),and best-corrected visual acuity (BCVA) were measured.Results:Macular edema responded well both anatomically and functionally to the TA injections.After the initial intravitreal injection,macular edema recurred at 2-4 months in the low-dose group (4 mg),at 3-5 months in the medium-dose group (8 mg),and at 6-9 months in the high-dose group (16 mg).No significant difference in BCVA or in foveal thickness were observed between the first intravitreal injection and the re-injection.There was no increase in IOP after re-injection of 16 mg TA,if the patient did not have an elevated IOP after the initial intravitreal injection of 4/8 mg TA.Conclusion:A low dosage of TA (4 mg) administered via intravitreal injection might be useful as an initial treatment for macular edema secondary to CRVO.A higher dosage of TA (16mg) can be used if there is no IOP elevation with the initial TA injection.

作者：Yong Wei；Huaizhou Wang；Fenghua Chen；Zhongqiao Zu；Chuncao Bi；Xinguang Yang 刊期： 2012年第03期

Purpose:To evaluate the diagnostic performance of the photopic negative response (PhNR) for the detection of primary open-angle glaucoma (POAG).Methods:Fifty-two normal subjects (52 eyes) and 173 POAG patients (173 eyes) were studied.The PhNR was elicited using a white stimuli on a white background.The mean deviation (MD) and pattern standard deviation (PSD) of the visual field were measured using standard automated perimetry (SAP).Spectral domain optical coherence tomography (SDOCT) was used to measure the mean thickness of the retinal nerve fiber layer (RNFL).Results:In the glaucoma group,as compared to the normal group,the amplitudes of a-waves,b-waves and PhNR were significantly smaller (P＜0.001),and the PhNR implicit time was significantly longer (P=0.004).The MD,PSD and mean thickness of the RNFL were significantly correlated with the amplitude of the PhNR (P＜0.001).The area under the receiver operating characteristic curve (AUCs) for the amplitudes of a-waves,b-waves and PhNR were 0.853,0.830 and 0.918,respectively.When the specificity was ≥95％,the sensitivities were 60.4％,54.2％ and 85.4％ respectively.Conclusion:The PhNR amplitude was reduced even when the loss in visual field sensitivity was mild,which suggests that PhNR might be a useful indicator of early glaucoma disease.

作者：Lina Huang；Xiaoli Shen；Ning Fan；Jing He 刊期： 2012年第03期

Purpose:To investigate gender differences in lens thickness (LT) and central anterior chamber depth (ACD) in normal subjects,and to assess age associated changes in these measures.Methods:The anterior chamber depth (ACD),and lens thickness (LT),of 150 normal subjects (150 eyes) was measured by anterior segment optical coherence tomography (ASOCT).Gender differences were assessed by independent ttest,and correlation analysis was used to examine the effect of Results:The mean values of ACD and LT were 2.69±0.32mm and 4.85±0.43 mm,respectively.Women had a significantly lower Mean ACD as compared to men (2.56±0.33 mm vs 2.85±0.29 mm; P ＜ 0.05).No statistically significant difference was found in LT between male and female subjects (P＞0.05).Correlation analysis findings suggest that LT increases with age (r=0.83,P ＜ 0.05),and that ACD decreases with age (r=-0.57,P ＜ 0.05).After controlling for LT,no significant correlation was observed between age and ACD (P＞0.05).Conclusion:The ACD of female subjects was,on average,shallower than that of their male counterparts.Aging was associated with increasing LT,and the observed narrowing of ACD with age,might be partially mediated by the increasing LT.

作者：Yangfa Zeng；Xing Liu；Tao Wang；Yimin Zhong；Jingjing Huang；Mingguang He 刊期： 2012年第03期

Purpose:Comparison of topical vs general aneasthesia for strabismus surgery.Methods:Preoperative patients (aged 6～12 years) were divided into two study groups:the topical aneasthesia group (n=22),and the general aneasthesia group (n=21).The study groups were compared on the following measures:analgesic effect,surgical correction effect,eye-heart reflex,preoperative preparation time.and operation time,using t-tests or X2tests where appropriate.Results:Compared with the general aneasthesia group,the topical aneasthesia group gained better surgical correction results(P＜0.05),had a lower rate of eye-heart reflex (P＜0.05),and had a shorter preoperative preparation time (P＜0.001).No significant difference was observed between the groups in terms of the analgesic effect or operation time (P＞0.05).Conclusion:Topical aneasthesia represents a safe and effective alternative to general aneasthesia for strabismus surgery in children.

作者：Xiaoping He；Lina Chen；Xinfu Pan；Huiyong Hu；Zhimin Shi 刊期： 2012年第03期