林绵辉；陈镇荣
INTRODUCTION Sleep- wake rhythm is isolated from day- night rhythm of natural world;Sleep depends on the regulation of special structure of central nerve system and correlated neurotransmitters.This paper mainly introduces the research progress of neurotransmitter correlated to sleep.It benefits the comprehension of physiology,pathology and pharmacology of sleep and recognition of sleep.
作者：初建平；孟昭义 刊期： 2003年第07期
AIM:To investigate the efficacy of huperzine A in treating child language delay and its side effects.METHODS:37 children with language delay and other developmental diseases from pediatric neurology out- patient department, who did not undergo any language rehabilitation,were treated with huperzine A 50 μ g bi- daily for more 3 months and then the efficacy and side effects observed.The follow- up was arranged to record the efficacy monthly.RESULTS:37 cases of 40 had undergone the whole course and the total efficiency was 68% (25/37). Language developments of other 12 cases were not improved significantly.Other 3 children were not included in because epilepsy were observed among them.CONCLUSION:This pilot trial result suggests that huperzine A has efficacy on child language delay but should be investigated further.Huperzine A may trigger seizure of language delay patients with epilepsy.
作者：廖建湘；陈黎；黄铁栓；李冰 刊期： 2003年第07期
INTRODUCTION In the medical service for people accepting resting therapy and senile cadres,some psychological misunderstanding of medication of the aged often are observed.Meantime,the problem of reasonable medication more and more cause attention of people.
作者：刘家寿；李秀琴；陈丽萍；林宏燕 刊期： 2003年第07期
INTRODUCTION It is reported 70%- 90% patients show dementia psychology and behavior in patients with aging dementia (AD),which are the main causes of hospitalization.Others can not understand AD patients who also can not understand the other persons affecting quality of nursing.So,to comprehend communication skills,to support them menally are very important for improvement of AD patients' quality of life.
作者：欧正红；黄丽葵；卢玉贞；孔容冰；马超 刊期： 2003年第07期
INTRODUCTION The headache of common nature as well as headachic epilepsy and hemicrania pianheadache often affects the children.Hemicrania is the result of mental and vascular disorder,which is examined with transcranial Doppler(TCD) and electroencephalography(EEG).In this study,we analyzed the characteristics of vascular headache of children compared with adults.
作者：孟庆荣 刊期： 2003年第07期
BACKGROUND:Therapy with block needle knife can block pain conduction pathway and prevent vicious cycle of pain, improve blood cirvulation and enhance inflammatory.With the help of needle knife, adhesion, keloid and muscles spasmed can be cut and isolated to active equilibarium of muscles around joints.
作者：张庆君；魏斌 刊期： 2003年第07期
目的探讨功能磁共振 (blood oxygenation level dependent functional MRI, BOLD fMRI)在临床医学方面的应用价值.方法对 1例右侧顶叶单发转移瘤患者在手术前、后分别进行了双侧动手试验的脑功能成像.结果脑功能成像准确地反映了运动功能激活区的位置及激活程度,肿瘤侧运动区可因肿瘤占位效应产生移位,手术前的手动试验潜在功能区并未被激活,但是在肿瘤切除术后,主运动区 M1以外可见潜在重组的功能区激活.结论脑内重要功能区肿瘤切除术患者,应常规进行术前和术后 fMRI的研究,这对于提高术后患者生活质量、避免医源性损伤或将其减至低水平有极大的帮助.
作者：张磊；金真；曾亚伟；王彦；郑冬；续元超 刊期： 2003年第07期
目的研究碱性成纤维细胞生长因子 (basic fibroblast growth factor, bFGF)在大鼠短暂大脑中动脉阻塞 (MCAO)再灌注后不同时点表达的变化,进一步探讨 bFGF对局灶性脑缺血的脑保护作用,为治疗缺血性脑血管病提供实验基础和依据.方法采用栓线法 MCAO动物模型 ,通过免疫组化方法观察 bFGF的表达情况.结果免疫阳性细胞主要在神经元和神经胶质细胞中的表达, bFGF在缺血再灌注后 6 h开始表达 ,1 d时达高峰 ,3 d时开始下降 , 7 d时有少量表达.结论短暂 MCAO后 bFGF表达上调 ,提示 bFGF的表达增加对缺血脑组织有保护作用.
作者：王静娥；张朝东 刊期： 2003年第07期
AIM:To observe the influence of psychological intervention on mental health of hemiplegias after stroke.METHODS:82 hemiplegias after stroke were divided into control and intervention groups in certain conditions.Patients in control group received only routine treatment,while patients in intervention group received psychological intervention as well.Symptom Checklist was adopted to measure the mental health of patients.RESULTS:The scores of panic,anxiety,depression and stubborn in intervention group were significantly lower than that in control(P< 0.05 or P< 0.01). CONCLUSION:Early psychological intervention can improve the mental health of hemiplegias after stroke.
作者：谢淑丽；朱明光；崔焕波；刘海燕 刊期： 2003年第07期
INTRODUCTION 856 cases of severe trachoma were treated from May 1984 by freezing combined with drugs,the effects were satisfying.
作者：于亚东；张东航；王永毅 刊期： 2003年第07期
作者： 刊期： 2003年第07期
INTRODUCTION Xingding is a compound agent of the fourth edition extract of ginkgo leaf,with addtion of agacore.Its main ingradient are ginkgo seed flavonoid glycoside(24% ), ginkgo seed lactone(3% ),bilobalide(3% ) and agacore(10% ).With ginkgo leaf acid smaller than 5× 10- 6,many clinical and basic research prove it has many biological effects.
作者：雷显泽；周妮；黄良国 刊期： 2003年第07期
INTRODUCTION The incidence,handicapping and fatality of cerebrovascular accidence (CVA) are high.Preventing complications and sequela, promoting function recovery, using remaining function adequately and regulating psychic state can promote patients self- care ability.
作者：楚平华 刊期： 2003年第07期
AIM:To estimate the prognosis of Bell palsy.METHODS: Blink reflex (BR), electromyography(EMG),motor latency(ML) and amplitude (AMP) of facial nerve were performed in 42 patients with Bell's palsy.The patients were followed about half a year.RESULTS: (1)When 1 of the 3R waves related with the ill side existed or appeared in 3 weeks after onset,97% patients could recover completely.The recovery time was related to the time of the occurrence of R wave.(2) When 1 of the 3 R waves appeared in the 4th week, 60% patients could recover completely.When none of the 3 waves appeared after the 4th week,100% patients could not recover completely.EMG showed spontaneous activities in 3 of the 6 patients in the 4th week.(3) Motor latency and amplitude of facial nerve were examined when the illness stopped developing.All patients had normal latencies.5 patients' amplitudes reduced more than 90% . 3 of the 5 patients did not appear the related R waves after the 4th week.CONCLUSION:BR might provide the early sign of good prognosis of Bell's palsy. BR together with EMG and ML and AMP of facial nerve might provide the later sign of poor prognosis.
作者：鲍海平；常宇；毛艺芳；尹琳；高政 刊期： 2003年第07期
INTRODUCTION Subhypothermic treatment is the most effective method for treatment of severe cranial injury and its application in clinic in recent years has achieved good effect.But some difficulties still need further exporation.
作者：张锦宏；王兴鹏 刊期： 2003年第07期
作者： 刊期： 2003年第07期
INTRODUCTION Postcranial- trauma headache is one of the most common symptoms in clinic.The earlier these symptoms are improved the more active effects will be obtained for the patients' recovery and prognosis. `
作者：杜安民；万从容 刊期： 2003年第07期
目的探讨单纤维肌电图 (SFEMG)在糖尿病周围神经病 (DPN)中的应用.方法 2型糖尿病患者 36例,采用 Viking IV肌电图仪,测定指总伸肌的颤抖和纤维密度 (FD),同时进行常规神经传导检测 (NCS)并测量空腹血糖和糖化血红蛋白 (HbA1c).结果颤抖和 FD具有相关性,且均与 HbA1c呈正相关.18例 NCS异常者,颤抖值均超出正常范围 (11例伴阻滞 ), 14例 FD增加; 18例 NCS正常者, 7例颤抖值增大 (3例伴阻滞 ), 5例 FD增加.结论颤抖和 FD所反映的失神经-神经再支配与代谢状况相关联; SFEMG是 DPN早期诊断的敏感手段,可发现亚临床神经病.
作者：王真真；陈文明；卢祖能；王镇涛；曾庆杏；聂传云 刊期： 2003年第07期
目的 ALEC(亚力克 )是由α-亚麻酸( A)、 L-赖氨酸( L)、维生素 E( E)及维生素 C( C)组成的复方,通过正交试验设计,以脑组织中乳酸含量为指标,确定 4者比例( A: L: E: C为 432: 187: 18: 8) ,研究 ALEC对大鼠在局限性缺血、缺氧状态下的脑细胞保护作用.方法用定量方法分析在体皮层脑电( ECoG)在正常供气与停止呼吸情况下的变化,采用电凝阻断一侧中动脉造成局限性脑缺血模型及判断药物的脑保护作用.结果 ALEC高、中、低 3个剂量组均能延长大鼠急性反复性缺氧皮层脑电消失 /振幅达低时间,缩短脑电恢复时间.ALEC可减少大鼠大脑中动脉梗死( MCAO) 24 h后海马 CA1区细胞死亡数.结论 ALEC对脑细胞具有保护作用.
作者：潘建春；宋培贞；库宝善 刊期： 2003年第07期
作者： 刊期： 2003年第07期
中国组织工程研究杂志
主管:中华人民共和国卫生部
主办：中国康复医学会,《中国组织工程研究与临床康复》杂志社
