AIM:To estimate the prognosis of Bell palsy.METHODS: Blink reflex (BR), electromyography(EMG),motor latency(ML) and amplitude (AMP) of facial nerve were performed in 42 patients with Bell's palsy.The patients were followed about half a year.RESULTS: (1)When 1 of the 3R waves related with the ill side existed or appeared in 3 weeks after onset,97% patients could recover completely.The recovery time was related to the time of the occurrence of R wave.(2) When 1 of the 3 R waves appeared in the 4th week, 60% patients could recover completely.When none of the 3 waves appeared after the 4th week,100% patients could not recover completely.EMG showed spontaneous activities in 3 of the 6 patients in the 4th week.(3) Motor latency and amplitude of facial nerve were examined when the illness stopped developing.All patients had normal latencies.5 patients' amplitudes reduced more than 90% . 3 of the 5 patients did not appear the related R waves after the 4th week.CONCLUSION:BR might provide the early sign of good prognosis of Bell's palsy. BR together with EMG and ML and AMP of facial nerve might provide the later sign of poor prognosis.
作者：鲍海平；常宇；毛艺芳；尹琳；高政 刊期： 2003年第07期
INTRODUCTION At present,ultrasonic doppler is used to examine blood circulation in big vessels in clinic,but there isn't still good and simple method for examination of blood circulation and vascular functions of limbs end and infrared thermography has some advantage in this aspect.It is well known that Raynaud phenomenon is caused by spasm and lesion of small end vessels of limbs.In clinic,provocation test might be used to provoke its onset and acknowledge of reaction condition of provocation in healthy people is the premise to judge abnormality and other lesions.
作者：张志强；苑秀华；沈艺莲；李少忠；俞澄；田丽君 刊期： 2003年第07期
BACKGROUND:Temporomandibular disorders ( TMD) included a group of clinical symptoms and disorder of masticate muscle group and temporomandibular joint,while its causes are not clear.TMD is characterized by pain around temporomandibular joi nt,sanp,and movement disorder in mandible,Currently,it is generally accepted that multiple factors resulted in TMD,including mental and psychological,muscular and tooth factors.Comprehensive treatment rather than single treatment is suggested for TMD.
作者：黄昊红；徐文华；李佐强；韩永红 刊期： 2003年第07期
BACKGROUND:Under the prerequisit of radical cure modern treatment of tumor need keep or rebuild functions of patients and improve their quality of life during the period of suvival.
作者：丁仕章；何玉芳；张镇平 刊期： 2003年第07期
AIM:To evaluate the diagnosis value of MRI for neurovascular compression (NVC) in trigeminal neuralgia(TN) and facial spasm(FS).METHODS:15 patients with TN and 2 patient with FS underwent SE T1WI and T2WI first, then 3D- TOF- SPGR sequences.RESULTS:NVC was found in all the patients, MRI findings were consistent with the surgical operative findings completely.CONCLUSION:It is considered to be of important to use MRI to find out the causes of TN and FS,especially to utilize the 3D- TOF- SPGR sequences, which may possess high sensitivity in determining NVC.
作者：公茂青；佟志勇；李喆；王运杰 刊期： 2003年第07期
路易体痴呆是神经变性痴呆中仅次于 Alzheimer病 (AD)居第二位的常见类型,约占痴呆的 15%～ 25%,已被公认为一个独立的疾病实体.与一般的单一疾病实体所不同的是,路易体痴呆包含了多种疾病的表现,其临床特征为波动性认知损伤 ,以视幻觉为主的精神症状和锥体外系症状,组织学必须满足大脑皮层及皮层下核团弥散分布的路易小体.由于路易体痴呆具有不同于其他变性痴呆疾病的病程、预后和治疗反应,因此准确的临床诊断和适当的管理措施如避免使用神经安定剂、合理正确的使用抗帕金森病 (PD)药物是临床医师的重要责任.
作者：解恒革 刊期： 2003年第07期
AIM:To analyze relationship between health quotient and mood stability of 202 cases of Department of Physical Education and 786 cases of public course 2000 in Shaanxi Normal University.METHODS:Mood stability and health quotient were surveyed through questionnaire for 202 students of physical department of grade 1998- 2001 and 286 of public lessons.RESULTS:Percent of students of physical departments with abnormal mood was lower than that of public lessons,more students with high score of mood stability for physical departments compared with public students.CONCLUSION:Quotients index has close relation with mood stability for students of physical department and public lessons.
作者：马亚妮；王保平；颜礼波 刊期： 2003年第07期
作者： 刊期： 2003年第07期
INTRODUCTION In the medical service for people accepting resting therapy and senile cadres,some psychological misunderstanding of medication of the aged often are observed.Meantime,the problem of reasonable medication more and more cause attention of people.
作者：刘家寿；李秀琴；陈丽萍；林宏燕 刊期： 2003年第07期
INTRODUCTION Recently,death rate of stroke acute stage decreased dramatically due to improvement of diagnosis,salvage and treatment in cerebral vascular.However,mutilation rate increased.In order to relieve disable and improve ability of daily life in stroke patients,early rehabilitation care should be taken in acute stroke patients to get better effects.
作者：逄桂英 刊期： 2003年第07期
INTRODUCTION Cerebrovascualr disease is common disease of senile nerve system, and is also main reason to epilepsy. Handicapping rate of cerebral stroke is high. There was few report on EEG and TCD of epilepsy after stroke.
作者：麦训良；叶小红；林玉兰 刊期： 2003年第07期
目的通过生育年龄吸毒女性及自愿受检非吸毒正常女性,从下丘脑生殖轴、外周血女性相关激素水平及临床症状体征 3个水平进行对比研究,以探讨长期使用海洛因对女性生殖系统的损害.方法填写调查表、对患者进行相关体检,抽血进行女性激素检测、阴道细胞涂片查雌激素影响程度或卵巢功能低下情况、妇科彩色 B超测量子宫及其内膜和卵巢大小.结果吸毒组促性腺激素释放激素( GnRH)、雌二醇( E2) 、孕酮( P)明显低于正常组,而卵泡刺激素( FSH)、黄体生成素( LH)相反明显高于正常组( P< 0.01及 < 0.05);与正常组比,吸毒组阴道雌激素水平降低、而阴道 pH值升高( P< 0.05);皮下脂肪减少、子宫、子宫内膜、卵巢、乳房、脂肪、大阴唇等明显萎缩( P< 0.05或 P< 0.01);另吸毒组多数显现月经紊乱、停经或闭经.结论长期使用海洛因可通过抑制生殖轴、抑制排卵及卵巢功能等途径,对女性生殖系统造成明显损害.长期吸毒可致卵巢功能减退甚至衰竭危险.
作者：严海燕；杨仁美；木兆慈；张秋红；李鹏；赖宏芳；杨一平；程玲；孙杏娟；王平华；李娜；骆跃 刊期： 2003年第07期
INTRODUCTION Before the growth and development of brain,or before or after birth, if the brain was injured by damage or injury,permanet,partial or all of the extremeties may harbor motor or positional abnormorlites. This kind of the abnormality is changed with the development of the infant.At the same time,there were different problems and priority development points at different growth stage and can be classified as infant age, school age and puberty age.
作者：王育庆；段俊峰；施凤玲 刊期： 2003年第07期
INTRODUCTION Knee osteoarthritis is a regenerated change of knee hyaline cartilage, complicated with bone hyperplasia,synovitis and articular capsule and muscle changes due to old age and knee joint injury, deformity and diseases etc factors.Osteoarthritis induced many clinical manifestations including knee ache,swelling and limited motion and seriously affected the quality of the patients'.
作者：徐振奇；姜贵云；刘旭东；柴叶红；李青 刊期： 2003年第07期
INTRODUCTION Sleep- wake rhythm is isolated from day- night rhythm of natural world;Sleep depends on the regulation of special structure of central nerve system and correlated neurotransmitters.This paper mainly introduces the research progress of neurotransmitter correlated to sleep.It benefits the comprehension of physiology,pathology and pharmacology of sleep and recognition of sleep.
作者：初建平；孟昭义 刊期： 2003年第07期
目的了解正常人颈动脉硬化患者及脑梗死患者血清同型半胱氨酸 (serum total nomocysteine,tHcy)水平及给予叶酸和维生素 B12治疗后血 tHcy含量的变化.方法脑梗死组 80例,男 71例,女 9例,年龄 63～ 80岁,平均 74岁,符合脑梗死的诊断标准,均在发病后 2周内测定 tHcy含量;颈动脉硬化组 80例,男 71例,女 9例,年龄 62～ 79岁,平均 72岁.双侧颈动脉 B超检查均存在颈动脉硬化及 (或 )粥样斑块.以上两组均除外甲状腺功能减退及肾功能减退.入选者在测定血清叶酸、维生素 B12、肌酐、血糖、血脂水平及血压和体重指数后,各组均随机分为两组,即干预治疗组及非干预治疗组,每组 40例.干预治疗组患者给予叶酸 1.25 mg,隔日 1次,维生素 B12 8 μ g, 1次 /d,口服 10个月后复查上述各项指标.结果治疗前 3组血 tHcy水平各不相同,脑梗死组为 (16± 5) μ mol/L,颈动脉硬化组为 (14± 5) μ mol/L,正常老年人组为 (12± 3) μ mol/L, 3组比较差异有显著意义.血 tHcy含量增高,叶酸水平越低.相关分析发现,血 tHcy水平与叶酸、维生素 B12呈负相关.干预治疗后,治疗组患者的血 tHcy含量均有所下降.结论不同程度的脑缺血性疾病与血 tHcy水平有一定的关系,补充营养元素有助于降低血 tHcy水平,以减少高 tHcy对血管的素性作用.
作者：黄延焱；卢晓喆；程梅芬 刊期： 2003年第07期
目的胰岛素样生长因子- 1(IGF- 1)已被证实具有神经营养和保护功能,然而对其在弥漫性脑损伤 (DBI)中的作用还知之甚少,该研究探讨 DBI后大鼠脑皮层 IGF- 1及其受体 (IGF- 1R)表达的变化及意义.方法用 Marmarou方法制作大鼠弥漫性脑损伤模型,用免疫组织化学方法观察伤后不同时间大鼠脑皮层 IGF- 1及 IGF- 1R的表达.结果致伤后皮层 IGF- 1阳性细胞数 3 d后开始增加, 7 d后达到高峰, 14 d后恢复正常水平; IGF- 1R表达在实验过程中无显著变化.结论 IGF- 1参与了 DBI的病理生理过程,可能为临床治疗重型颅脑损伤提供新的理论依据.
作者：苏军；章翔；吴景文 刊期： 2003年第07期
为了解早期康复治疗对急性脑卒中患者偏瘫上肢愈后的影响,对 24例急性脑卒中患者在神经内科常规治疗基础上加早期康复治疗,观察患者上肢运动功能恢复方面的效果.结果证明早期康复治疗对脑卒中患者的上肢功能恢复有益.
作者：张辉；王毳 刊期： 2003年第07期
脑损害患者存在的语义范畴特异性损伤现象激发了人们对语义知识神经表征规则的研究.传统的神经心理学检查法及功能成像技术是研究语义记忆神经基础的主要方法.神经心理学是通过研究患者脑损伤部位与其损伤的语义知识范畴间的关系来推断语义知识的神经基础;而功能成像技术是通过直接检测正常人在提取各范畴语义知识时的脑活动模式来揭示语义知识的神经基础.因此,作为语义记忆探测材料的认知任务的设置直接影响到研究的效度与结果.因各研究所用的认知任务不同,研究结果与结论也呈现出较大的分歧,部分学者认为语义记忆是一单一的统一体,但部分学者认为语义记忆是一由类别子系统或是通道子系统组成的集合体.
作者：金花；莫雷；陈卓铭 刊期： 2003年第07期
目的研究 caspase- 3抑制剂 Ac- DEVD- CMK及 calpain抑制剂 ALLN干预治疗对大鼠局灶性脑缺血 /再灌注模型的神经保护作用.方法经左侧侧脑室注射 DEVD或 /和 ALLN及溶剂二甲基亚砜( DMSO)后,制作大鼠左侧 MCA缺血再灌注模型;缺血 2 h再灌注 24 h进行 TTC染色观察梗死灶的形成情况;并分别于缺血 2 h再灌注 24 h或 48 h检测鼠脑中单、双链 DNA断裂情况.结果溶剂 DMSO预处理组的各项指标与 MCAO模型组无明显差异; DEVD或 ALLN治疗后缺血侧脑中 Klenow及 TUNEL阳性细胞数均明显减少,二者合用作用强.结论 Caspase- 3与 calpain均在缺血性脑损伤中起重要作用,对此进行治疗干预具有潜在的临床应用价值.
作者：王宇卉；卞杰勇；强华；夏春林；邵福源 刊期： 2003年第07期
中国组织工程研究杂志
主管:中华人民共和国卫生部
主办：中国康复医学会,《中国组织工程研究与临床康复》杂志社
