金花；莫雷；陈卓铭
BACKGROUND:In China,steroid such as dexamethasone was often used for curing multiple sclerosis(MS),which had definitive effect but was slow in effect and needed a long time for taking medicine,more importantly,had severe side- effect.In recent years,high dose methylprednisolone has achieved some effect on immuno- neurologic diseases.
作者：陈运平；孙圣刚；梅元武 刊期： 2003年第07期
目的口吃者言语产出自动化问题是多年来理论的关键问题之一,研究此问题可揭示大脑言语产生的作用机制,并对口吃矫正的理论和方法具有实际的应用意义.方法应用双任务探测反应时的行为实验范式,通过复杂性不同的单字实验和两字实验,分别检测了 22例发展性口吃者在朗读和默读汉字两种阅读状态下探测任务(语音搜索和语音比较)的按键反应时.结果朗读状态下探测任务的反应时在单字和两字实验中都较默读状态延长,其中单字实验中的差异有显著性意义( P< 0.05),两字实验中的差异有非常显著性意义( P< 0.001);而且单字与双字语音产出时间(朗读与默读探测反应时之差异量)的比较具有显著性( P< 0.01),表明两字朗读状态下语音产出反应时较单字明显延长.结论发展性口吃者朗读时的语音产出为一种自动化程度较低的控制性加工,言语复杂性增加使不流利言语增多可能与语音产出需要的注意资源增加有关.
作者：宋鲁平；宁宁；彭聃龄；解蕾；张兆利；黄永旺 刊期： 2003年第07期
BACKGROUND:Children cerebral palsy not only affects the quality of the affected children's lives but also burdens the family and the society heavily.Therefore, analysis of the disease and its causes from the viewpoint of clinic might helpful in treatment and prevention of the disease.
作者：赵蒙 刊期： 2003年第07期
作者： 刊期： 2003年第07期
INTRODUCTION The objective of resist coagulating treatment is prevent a spread of thrombus and new thrombus form, hasten a connect again of vein and in same is an assistant treatment for dissolve thrombus and operation.It is the first way presently that dissolve thrombus cure DVT.
作者：金辉；胡中；杨斌；金勇 刊期： 2003年第07期
INTRODUCTION Peripheral nerve lesion resulting from drug toxicity is caused by drugs which interrupt some enzymes in process of nervous metabolism and lead to loss of myelin sheath or axis- cylinder degeneration. Some drugs used in clinic can lead to peripheral nerve lesion. Patients showed symptoms such as numbness, asthenia.
作者：张昆林；马莎；毛小川 刊期： 2003年第07期
INTRODUCTION The incidence,handicapping and fatality of cerebrovascular accidence (CVA) are high.Preventing complications and sequela, promoting function recovery, using remaining function adequately and regulating psychic state can promote patients self- care ability.
作者：楚平华 刊期： 2003年第07期
MATERIALS AND METHODS Materials 42 cases of female patients were client from hospital,with age ranging from 38 to 55 years(average 46 years).Disease course was franging from 0.5 to 6.0 years.
作者：谢珍 刊期： 2003年第07期
INTRODUCTION It has been proved recently that obesity, microalbuminuria (MAU) and low- insulin resistance are independent risk factors and increase the mortality of cardiovascular diseases in type 2 diabetic patients. In order to study the relationship between microalbuminria and early larger artery lesions in type 2 diabetic patients,we analyzed the relationship between urine albumin excretory rate and arterial hemodynamic change in lower limbs.
作者：何伟民；郭树龙；林毅辉 刊期： 2003年第07期
BACKGROUND:Acute myocardiar infarction(AMI)threaten patients' life.Alteration of life modes,disease,risk of family life,economic and occupational stress all contribute to psychological disorder,anxiety,horror in myoinfarction.
作者：刘娟 刊期： 2003年第07期
随着 133Xe吸入法测定局部脑血流量( topical cerebral blood flow,rCBF)的检查手段普遍推广应用,采用此法对持续性植物状态( persistent vegetative state, PVS)患者进行 rCBF测定.并对结果进行分析,从而进一步探讨 PVS患者不同病因、病情变化的 rCBF改变情况及机制分析.
作者：吴春平；陈立；马虎龙；王培东 刊期： 2003年第07期
BACKGROUND:Magnetopolarization quantum blood QOG treatment means using auto- venous blood or other people's blood of same type 150 to 200 ml and transferring back to body after external anticoagulation.
作者：张谦；郑世文 刊期： 2003年第07期
INTRODUCTION Recently,death rate of stroke acute stage decreased dramatically due to improvement of diagnosis,salvage and treatment in cerebral vascular.However,mutilation rate increased.In order to relieve disable and improve ability of daily life in stroke patients,early rehabilitation care should be taken in acute stroke patients to get better effects.
作者：逄桂英 刊期： 2003年第07期
目的遗传性脊髓小脑共济失调 7型( SCA7)是 SCA系列中首个确定累及视网膜的疾病,该研究探讨中国 SCA7的临床特点.方法对一个表现为视力下降、辩色力异常和共济失调的 SCA7家系 23例成员( 8例患者)进行了系统的家系调查、体格检查及头颅 MR、眼底照相、视觉诱发电位、视网膜电流图等有关的辅助检查,结合国内外文献总结 SCA7临床特点.结果该家系为常染色体显性遗传,多数患者视力损害先于共济失调,存在视网膜色素变性 , 为蓝-黄色盲或蓝色盲,无夜盲,无智能减退.结论中国 SCA7患者临床表型存在多样性.
作者：韩燕；郑惠民；丁素菊；蒋建明；余龙；黄兴华；马丽杰 刊期： 2003年第07期
近年来国内外研究资料表明,小脑顶核( fastigial nucleus,FN)可能在脑血流量的调节方面具有重要作用 [1],顶核电刺激( fastigial nucleus stimulation,FNS)可增加大脑血流量 [2].椎基底动脉供血不足是神经科常见的一组以眩晕为主要临床表现的缺血性脑血管疾病,临床治疗主要采用扩血管、活血化瘀类药物治疗,在药物治疗的基础上采用电刺激小脑顶核治疗椎基底动脉供血不足并观察治疗前后脑血流速度的变化与平均住院天数,以探讨 FNS在椎基底动脉供血不足治疗中的应用价值.
作者：李亚新；阎平建 刊期： 2003年第07期
INTRODUCTION 856 cases of severe trachoma were treated from May 1984 by freezing combined with drugs,the effects were satisfying.
作者：于亚东；张东航；王永毅 刊期： 2003年第07期
AIM:To observe the expression of vascular endothelial growth factor(VEGF) and Factor VIII related antigen(FVIII- R Ag) in rats brain tissue in the border zone of the hematoma,and explore the relationship between the expression of VEGF and the brain angionesis after intracerebral hmorrhage(ICH). METHODS:Rat of model of ICH was induced by injection of collagenase physiological saline into the right caudate nucleus.The immunohistochemical methods were performed by using different antisera of VEGF and FVIII- R Ag in serial sections of rats brain at 12 h,1 d,3 d and 7 d after ICH respectively.RESULTS:The amount of VEGF positive cells was markedly increased,and reached the highest at 7th day in the border zone after ICG(P< 0.01),but there were no significant difference among the mean value of A of cells at different time points (P >0.05).Compared with the controls,both the FVIII- R Ag positive endothelial cells and the A of cells were significantly different in experimental ICH goups after 1 day.CONCLUSION:The upregulated expression of VEGF might induce proliferation of endothelial cell and angiogenesis in the border zone after ICH in rats.
作者：揣兰香；张微微；戴卫平 刊期： 2003年第07期
AIM:To estimate the prognosis of Bell palsy.METHODS: Blink reflex (BR), electromyography(EMG),motor latency(ML) and amplitude (AMP) of facial nerve were performed in 42 patients with Bell's palsy.The patients were followed about half a year.RESULTS: (1)When 1 of the 3R waves related with the ill side existed or appeared in 3 weeks after onset,97% patients could recover completely.The recovery time was related to the time of the occurrence of R wave.(2) When 1 of the 3 R waves appeared in the 4th week, 60% patients could recover completely.When none of the 3 waves appeared after the 4th week,100% patients could not recover completely.EMG showed spontaneous activities in 3 of the 6 patients in the 4th week.(3) Motor latency and amplitude of facial nerve were examined when the illness stopped developing.All patients had normal latencies.5 patients' amplitudes reduced more than 90% . 3 of the 5 patients did not appear the related R waves after the 4th week.CONCLUSION:BR might provide the early sign of good prognosis of Bell's palsy. BR together with EMG and ML and AMP of facial nerve might provide the later sign of poor prognosis.
作者：鲍海平；常宇；毛艺芳；尹琳；高政 刊期： 2003年第07期
目的研究碱性成纤维细胞生长因子 (basic fibroblast growth factor, bFGF)在大鼠短暂大脑中动脉阻塞 (MCAO)再灌注后不同时点表达的变化,进一步探讨 bFGF对局灶性脑缺血的脑保护作用,为治疗缺血性脑血管病提供实验基础和依据.方法采用栓线法 MCAO动物模型 ,通过免疫组化方法观察 bFGF的表达情况.结果免疫阳性细胞主要在神经元和神经胶质细胞中的表达, bFGF在缺血再灌注后 6 h开始表达 ,1 d时达高峰 ,3 d时开始下降 , 7 d时有少量表达.结论短暂 MCAO后 bFGF表达上调 ,提示 bFGF的表达增加对缺血脑组织有保护作用.
作者：王静娥；张朝东 刊期： 2003年第07期
INTRODUCTION Poems dyndrom is a kind of rarely seen clinical symptomes with multiple system impairment,including polyneuropathy, swelling of organs,endocrine disorder,M protein and skin lesions.Other symptoms including anasarca,profuse sweating,hippocratic nails and low febrile.
作者：陈玮；锁海虹；赵琳；王桂荣 刊期： 2003年第07期
中国组织工程研究杂志
主管:中华人民共和国卫生部
主办：中国康复医学会,《中国组织工程研究与临床康复》杂志社
