潘建春；宋培贞；库宝善
BACKGROUND:To the patients with systemic lupus erythematosus(SLE) combined with leukopenia and thrombocytopenia,psychological therapy and rehabilitation nursing have some effect on rehabilitation of patients while patients are treated with pharmacotherapy such as glucocorticoid hormone and immunosuppressant.
作者：苏庆芬；陈秀梅；叶凤珍 刊期： 2003年第07期
目的探讨功能磁共振 (blood oxygenation level dependent functional MRI, BOLD fMRI)在临床医学方面的应用价值.方法对 1例右侧顶叶单发转移瘤患者在手术前、后分别进行了双侧动手试验的脑功能成像.结果脑功能成像准确地反映了运动功能激活区的位置及激活程度,肿瘤侧运动区可因肿瘤占位效应产生移位,手术前的手动试验潜在功能区并未被激活,但是在肿瘤切除术后,主运动区 M1以外可见潜在重组的功能区激活.结论脑内重要功能区肿瘤切除术患者,应常规进行术前和术后 fMRI的研究,这对于提高术后患者生活质量、避免医源性损伤或将其减至低水平有极大的帮助.
作者：张磊；金真；曾亚伟；王彦；郑冬；续元超 刊期： 2003年第07期
INTRODUCTION:Shoulder- hand syndrome(SHS) also called reflective sympathetic malnutrition is a common syndrome and often seen in stroke paralysis,which early manifestation is sudden edema of hand,pain,increased skin temperature,shoulder pain.If treatment is prolonged,muscle atrophy of hand and permanent loss of range of movement might occure.Comprehensive rehabilitation treatment has a good effect on SHS.In this article,effect of block of ganglion stellatum on SHS is observed on base of comprehensive rehabilitation treatment.
作者：曾西；陈尚康；关晨霞；姜丽；王留根 刊期： 2003年第07期
目的遗传性脊髓小脑共济失调 7型( SCA7)是 SCA系列中首个确定累及视网膜的疾病,该研究探讨中国 SCA7的临床特点.方法对一个表现为视力下降、辩色力异常和共济失调的 SCA7家系 23例成员( 8例患者)进行了系统的家系调查、体格检查及头颅 MR、眼底照相、视觉诱发电位、视网膜电流图等有关的辅助检查,结合国内外文献总结 SCA7临床特点.结果该家系为常染色体显性遗传,多数患者视力损害先于共济失调,存在视网膜色素变性 , 为蓝-黄色盲或蓝色盲,无夜盲,无智能减退.结论中国 SCA7患者临床表型存在多样性.
作者：韩燕；郑惠民；丁素菊；蒋建明；余龙；黄兴华；马丽杰 刊期： 2003年第07期
BACKGROUND:In China,steroid such as dexamethasone was often used for curing multiple sclerosis(MS),which had definitive effect but was slow in effect and needed a long time for taking medicine,more importantly,had severe side- effect.In recent years,high dose methylprednisolone has achieved some effect on immuno- neurologic diseases.
作者：陈运平；孙圣刚；梅元武 刊期： 2003年第07期
手足徐动是中医肝肾不足、虚风内动、风痰上扰的表现,治疗即要化痰熄风又要兼顾补肝肾之不足.用中药汤剂半夏白术天麻汤合六味地黄丸加减口服可以滋阴化痰熄风,温灸百会、风府以振奋阳气于阳中求阴,穴位注射药物营养神经.治疗手足徐动型脑性瘫痪取得了较好的疗效.
作者：刘卫民；袁海斌；黄笑；周雪娇 刊期： 2003年第07期
AIM:To observe the expression of vascular endothelial growth factor(VEGF) and Factor VIII related antigen(FVIII- R Ag) in rats brain tissue in the border zone of the hematoma,and explore the relationship between the expression of VEGF and the brain angionesis after intracerebral hmorrhage(ICH). METHODS:Rat of model of ICH was induced by injection of collagenase physiological saline into the right caudate nucleus.The immunohistochemical methods were performed by using different antisera of VEGF and FVIII- R Ag in serial sections of rats brain at 12 h,1 d,3 d and 7 d after ICH respectively.RESULTS:The amount of VEGF positive cells was markedly increased,and reached the highest at 7th day in the border zone after ICG(P< 0.01),but there were no significant difference among the mean value of A of cells at different time points (P >0.05).Compared with the controls,both the FVIII- R Ag positive endothelial cells and the A of cells were significantly different in experimental ICH goups after 1 day.CONCLUSION:The upregulated expression of VEGF might induce proliferation of endothelial cell and angiogenesis in the border zone after ICH in rats.
作者：揣兰香；张微微；戴卫平 刊期： 2003年第07期
INTRODUCTION Neurotrophic drugs,resting treatment,and proper physical therapy are generally suggested for rehabilitation after head trauma.In recent years,hyperbaric oxygen a new,safe and effective therapy had been used for rehabilitation following head trauma,which is safe,and effective.
作者：周宏图；王建宏；袁建国；张雪春 刊期： 2003年第07期
随着 133Xe吸入法测定局部脑血流量( topical cerebral blood flow,rCBF)的检查手段普遍推广应用,采用此法对持续性植物状态( persistent vegetative state, PVS)患者进行 rCBF测定.并对结果进行分析,从而进一步探讨 PVS患者不同病因、病情变化的 rCBF改变情况及机制分析.
作者：吴春平；陈立；马虎龙；王培东 刊期： 2003年第07期
目的通过生育年龄吸毒女性及自愿受检非吸毒正常女性,从下丘脑生殖轴、外周血女性相关激素水平及临床症状体征 3个水平进行对比研究,以探讨长期使用海洛因对女性生殖系统的损害.方法填写调查表、对患者进行相关体检,抽血进行女性激素检测、阴道细胞涂片查雌激素影响程度或卵巢功能低下情况、妇科彩色 B超测量子宫及其内膜和卵巢大小.结果吸毒组促性腺激素释放激素( GnRH)、雌二醇( E2) 、孕酮( P)明显低于正常组,而卵泡刺激素( FSH)、黄体生成素( LH)相反明显高于正常组( P< 0.01及 < 0.05);与正常组比,吸毒组阴道雌激素水平降低、而阴道 pH值升高( P< 0.05);皮下脂肪减少、子宫、子宫内膜、卵巢、乳房、脂肪、大阴唇等明显萎缩( P< 0.05或 P< 0.01);另吸毒组多数显现月经紊乱、停经或闭经.结论长期使用海洛因可通过抑制生殖轴、抑制排卵及卵巢功能等途径,对女性生殖系统造成明显损害.长期吸毒可致卵巢功能减退甚至衰竭危险.
作者：严海燕；杨仁美；木兆慈；张秋红；李鹏；赖宏芳；杨一平；程玲；孙杏娟；王平华；李娜；骆跃 刊期： 2003年第07期
INTRODUCTION Subhypothermic treatment is the most effective method for treatment of severe cranial injury and its application in clinic in recent years has achieved good effect.But some difficulties still need further exporation.
作者：张锦宏；王兴鹏 刊期： 2003年第07期
BACKGROUND:Motor obstacle of limbs directly resulted from hemiplegia after stroke seriously affect patients′ daily work and living.Conventional medicine treatment can improve the function of hemiplegic limbs at some degree, but more and more studies confirm that conventional acupuncture therapy is an effective method to improve motor function of limbs.By point stimulating channel system, acupuncture therapy can regulate qi and smooth channel system, thus regulate whole body to achieve the goal of curing hemiplegia. Acupuncture combined with hyperbaric oxygen therapy can accelerate regeneration of cerebral cells, and promote the recovery of motor function of paralyzed limbs.
作者：张志刚；孙毓 刊期： 2003年第07期
目的胰岛素样生长因子- 1(IGF- 1)已被证实具有神经营养和保护功能,然而对其在弥漫性脑损伤 (DBI)中的作用还知之甚少,该研究探讨 DBI后大鼠脑皮层 IGF- 1及其受体 (IGF- 1R)表达的变化及意义.方法用 Marmarou方法制作大鼠弥漫性脑损伤模型,用免疫组织化学方法观察伤后不同时间大鼠脑皮层 IGF- 1及 IGF- 1R的表达.结果致伤后皮层 IGF- 1阳性细胞数 3 d后开始增加, 7 d后达到高峰, 14 d后恢复正常水平; IGF- 1R表达在实验过程中无显著变化.结论 IGF- 1参与了 DBI的病理生理过程,可能为临床治疗重型颅脑损伤提供新的理论依据.
作者：苏军；章翔；吴景文 刊期： 2003年第07期
针刺改善脑卒中后肢体功能障碍已有大量临床报道,以灯盏花素穴位注射方法用于脑卒中肢体功能障碍的治疗,检验水针疗法改善脑卒中后肢体功能障碍的疗法优于单纯针刺的假设.
作者：李颖 刊期： 2003年第07期
路易体痴呆是神经变性痴呆中仅次于 Alzheimer病 (AD)居第二位的常见类型,约占痴呆的 15%～ 25%,已被公认为一个独立的疾病实体.与一般的单一疾病实体所不同的是,路易体痴呆包含了多种疾病的表现,其临床特征为波动性认知损伤 ,以视幻觉为主的精神症状和锥体外系症状,组织学必须满足大脑皮层及皮层下核团弥散分布的路易小体.由于路易体痴呆具有不同于其他变性痴呆疾病的病程、预后和治疗反应,因此准确的临床诊断和适当的管理措施如避免使用神经安定剂、合理正确的使用抗帕金森病 (PD)药物是临床医师的重要责任.
作者：解恒革 刊期： 2003年第07期
BACKGROUND:Brain stem auditory evoked potential(BAEP) can objectively reflex nerve conduction function of auricular conduction pathway and indirectively reflex functional status of the brain stem.
作者：魏明辉；王玉洁；姜新；陈晓虹 刊期： 2003年第07期
INTRODUCTION At present,ultrasonic doppler is used to examine blood circulation in big vessels in clinic,but there isn't still good and simple method for examination of blood circulation and vascular functions of limbs end and infrared thermography has some advantage in this aspect.It is well known that Raynaud phenomenon is caused by spasm and lesion of small end vessels of limbs.In clinic,provocation test might be used to provoke its onset and acknowledge of reaction condition of provocation in healthy people is the premise to judge abnormality and other lesions.
作者：张志强；苑秀华；沈艺莲；李少忠；俞澄；田丽君 刊期： 2003年第07期
INTRODUCTION Patients in rehabilitation department were mostly transferred from internal neurology department.With short course and stalbe conditions,if the patients were treated with on time and activated routine rehabilitation therapy,nerve cells not injured can establish normal connections and cause rehabilitation of the hemiplegia extremities and reduce or eliminated the disable degree of the patients.
作者：尹虹；田玉波 刊期： 2003年第07期
MATERIALS AND METHODS Materials 42 cases of female patients were client from hospital,with age ranging from 38 to 55 years(average 46 years).Disease course was franging from 0.5 to 6.0 years.
作者：谢珍 刊期： 2003年第07期
AIM:Discuss the relationship of pulse pressure and left ventricular function in hypertensive patients.METHODS:We observed the relationship of the pulse pressure and the times of again occurred coronary artery diseases, left ventricular fore and after span, left ventricular back wall thickness and left ventricular ejection fraction(EF) by color Doppler ultrasound in hypertensive patients. RESULTS:The times of again occurred coronary artery diseases, the left ventricular fore and after span and left ventricular EF of each pulse pressure group were significantly difference(P< 0.05, P< 0.01). CONCLUSION:The pulse pressure may take part in the further impair of left ventricular function coronary artery diseases.Control the pulse pressure coronary artery diseases have an important meaning in decreasing the further impair of left ventricular function.
作者：杨文；王浩；刘志发 刊期： 2003年第07期
中国组织工程研究杂志
主管:中华人民共和国卫生部
主办：中国康复医学会,《中国组织工程研究与临床康复》杂志社
