尹虹；田玉波
目的了解正常人颈动脉硬化患者及脑梗死患者血清同型半胱氨酸 (serum total nomocysteine,tHcy)水平及给予叶酸和维生素 B12治疗后血 tHcy含量的变化.方法脑梗死组 80例,男 71例,女 9例,年龄 63～ 80岁,平均 74岁,符合脑梗死的诊断标准,均在发病后 2周内测定 tHcy含量;颈动脉硬化组 80例,男 71例,女 9例,年龄 62～ 79岁,平均 72岁.双侧颈动脉 B超检查均存在颈动脉硬化及 (或 )粥样斑块.以上两组均除外甲状腺功能减退及肾功能减退.入选者在测定血清叶酸、维生素 B12、肌酐、血糖、血脂水平及血压和体重指数后,各组均随机分为两组,即干预治疗组及非干预治疗组,每组 40例.干预治疗组患者给予叶酸 1.25 mg,隔日 1次,维生素 B12 8 μ g, 1次 /d,口服 10个月后复查上述各项指标.结果治疗前 3组血 tHcy水平各不相同,脑梗死组为 (16± 5) μ mol/L,颈动脉硬化组为 (14± 5) μ mol/L,正常老年人组为 (12± 3) μ mol/L, 3组比较差异有显著意义.血 tHcy含量增高,叶酸水平越低.相关分析发现,血 tHcy水平与叶酸、维生素 B12呈负相关.干预治疗后,治疗组患者的血 tHcy含量均有所下降.结论不同程度的脑缺血性疾病与血 tHcy水平有一定的关系,补充营养元素有助于降低血 tHcy水平,以减少高 tHcy对血管的素性作用.
作者：黄延焱；卢晓喆；程梅芬 刊期： 2003年第07期
对于前庭系统性眩晕,仅靠临床表现来判断病变部位有无器质性损害,容易出差错.应用神经电生理检查,显示电生理改变,是否对临床医生有指导作用?为此,对前庭系统性眩晕患者进行脑干听觉诱电位( BAEP)检测,结合影像学资料及住院观察其转归情况,分析 BAEP的临床应用价值.
作者：吴振东；周宏君；李壮丰；陈汉波 刊期： 2003年第07期
BACKGROUND:In China,steroid such as dexamethasone was often used for curing multiple sclerosis(MS),which had definitive effect but was slow in effect and needed a long time for taking medicine,more importantly,had severe side- effect.In recent years,high dose methylprednisolone has achieved some effect on immuno- neurologic diseases.
作者：陈运平；孙圣刚；梅元武 刊期： 2003年第07期
目的通过生育年龄吸毒女性及自愿受检非吸毒正常女性,从下丘脑生殖轴、外周血女性相关激素水平及临床症状体征 3个水平进行对比研究,以探讨长期使用海洛因对女性生殖系统的损害.方法填写调查表、对患者进行相关体检,抽血进行女性激素检测、阴道细胞涂片查雌激素影响程度或卵巢功能低下情况、妇科彩色 B超测量子宫及其内膜和卵巢大小.结果吸毒组促性腺激素释放激素( GnRH)、雌二醇( E2) 、孕酮( P)明显低于正常组,而卵泡刺激素( FSH)、黄体生成素( LH)相反明显高于正常组( P< 0.01及 < 0.05);与正常组比,吸毒组阴道雌激素水平降低、而阴道 pH值升高( P< 0.05);皮下脂肪减少、子宫、子宫内膜、卵巢、乳房、脂肪、大阴唇等明显萎缩( P< 0.05或 P< 0.01);另吸毒组多数显现月经紊乱、停经或闭经.结论长期使用海洛因可通过抑制生殖轴、抑制排卵及卵巢功能等途径,对女性生殖系统造成明显损害.长期吸毒可致卵巢功能减退甚至衰竭危险.
作者：严海燕；杨仁美；木兆慈；张秋红；李鹏；赖宏芳；杨一平；程玲；孙杏娟；王平华；李娜；骆跃 刊期： 2003年第07期
BACKGROUND:Therapy with block needle knife can block pain conduction pathway and prevent vicious cycle of pain, improve blood cirvulation and enhance inflammatory.With the help of needle knife, adhesion, keloid and muscles spasmed can be cut and isolated to active equilibarium of muscles around joints.
作者：张庆君；魏斌 刊期： 2003年第07期
MATERIALS AND METHODS Materials 2 cases were diagnosed as arrhythmia without clear reasons by ECG and were confirmed that they didn't suffered organic diseases.All the cases received anti- arrhythmia and heart muscle nutrition drugs and didn't gain good effects.
作者：林绵辉；陈镇荣 刊期： 2003年第07期
INTRODUCTION Postcranial- trauma headache is one of the most common symptoms in clinic.The earlier these symptoms are improved the more active effects will be obtained for the patients' recovery and prognosis. `
作者：杜安民；万从容 刊期： 2003年第07期
AIM:To estimate the prognosis of Bell palsy.METHODS: Blink reflex (BR), electromyography(EMG),motor latency(ML) and amplitude (AMP) of facial nerve were performed in 42 patients with Bell's palsy.The patients were followed about half a year.RESULTS: (1)When 1 of the 3R waves related with the ill side existed or appeared in 3 weeks after onset,97% patients could recover completely.The recovery time was related to the time of the occurrence of R wave.(2) When 1 of the 3 R waves appeared in the 4th week, 60% patients could recover completely.When none of the 3 waves appeared after the 4th week,100% patients could not recover completely.EMG showed spontaneous activities in 3 of the 6 patients in the 4th week.(3) Motor latency and amplitude of facial nerve were examined when the illness stopped developing.All patients had normal latencies.5 patients' amplitudes reduced more than 90% . 3 of the 5 patients did not appear the related R waves after the 4th week.CONCLUSION:BR might provide the early sign of good prognosis of Bell's palsy. BR together with EMG and ML and AMP of facial nerve might provide the later sign of poor prognosis.
作者：鲍海平；常宇；毛艺芳；尹琳；高政 刊期： 2003年第07期
AIM:Abnormal transparent septum is common in clinical works but little in meaning,so some CT reports are not listed.We collected complete abnormal transparent septum cases to perform comparison analysis between CT diagnosis and clinical data.METHODS:109 abnormal transparent septum diagnosed by CT was compared with symptom of clinics.Axis scanning and no enhanced scanning were used in CT and 2 doctors in charge of sample collection.The 109 cases were excluded with abnormal transparent septum induced by secondary local cerebral atrophy and secondary perforation deformity.RESULTS:There were 15 cases with the fifth ventricle of cerebrum and 22 cases with the fifth and sixth ventricle of cerebrums,10 cases with transparent septum cyst,28 cases with translocation of transparent septum,8 cases with no crack in the forebrain,6 cases with poor development of keratoma and 20 cases of other deformity.CONCLUSION:Abnormal transparent septum cannot be omitted and should be clearly diagnosed by CT.
作者：曹连义；张勇 刊期： 2003年第07期
INTRODUCTION Because nasopharynx is near to base of skull,radiation therapy might cause radiating brain injury that will influence patient's life quality.
作者：彭慧平；卢晓欣；汤永建 刊期： 2003年第07期
目的言语测听在助听器的选配中有决定性的作用,中国临床应用较少,通过言语测听了解耳内式助听器和耳背式助听器的使用者在言语分辨率的差别.方法采用开放法和闭合法 ,分别对耳内式、耳背式助听器使用者,进行单耳聆听条件下的言语测试.言语信号类型选用单音节词和双音节词,每耳测听单音节词和双音节词各为 20个.结果耳内式、耳背式助听器使用者的使用效果相比,在言语分辨率上无论开放式、闭合式对双音节词、单音节词的分辨率无显著性差异( P >0.05);双音节词和单音节词的分辨率比较,开放式的状态下,有显著性差异( P< 0.05);闭合式的状态下,无显著差异( P >0.05).结论在助听器的选配中言语测听的实际实施受诸多因素的影响.
作者：高建林；杨月珍；梁晨；王晓阳；吴竹梅；杨丽 刊期： 2003年第07期
AIM:To observe the influence of psychological intervention on mental health of hemiplegias after stroke.METHODS:82 hemiplegias after stroke were divided into control and intervention groups in certain conditions.Patients in control group received only routine treatment,while patients in intervention group received psychological intervention as well.Symptom Checklist was adopted to measure the mental health of patients.RESULTS:The scores of panic,anxiety,depression and stubborn in intervention group were significantly lower than that in control(P< 0.05 or P< 0.01). CONCLUSION:Early psychological intervention can improve the mental health of hemiplegias after stroke.
作者：谢淑丽；朱明光；崔焕波；刘海燕 刊期： 2003年第07期
目的研究碱性成纤维细胞生长因子 (basic fibroblast growth factor, bFGF)在大鼠短暂大脑中动脉阻塞 (MCAO)再灌注后不同时点表达的变化,进一步探讨 bFGF对局灶性脑缺血的脑保护作用,为治疗缺血性脑血管病提供实验基础和依据.方法采用栓线法 MCAO动物模型 ,通过免疫组化方法观察 bFGF的表达情况.结果免疫阳性细胞主要在神经元和神经胶质细胞中的表达, bFGF在缺血再灌注后 6 h开始表达 ,1 d时达高峰 ,3 d时开始下降 , 7 d时有少量表达.结论短暂 MCAO后 bFGF表达上调 ,提示 bFGF的表达增加对缺血脑组织有保护作用.
作者：王静娥；张朝东 刊期： 2003年第07期
缝隙连接( gap junction, GJ)是相邻细胞间直接交流胞质成分进行通讯的唯一通道.中枢神经系统神经元间 GJ通讯涉及许多生理及病理的过程,其通道的开-关与神经损伤的修复、癫痫的发作、记忆的形成与再现、肌痉挛的发生等均密切相关.因此,通过了解调节 GJ开-关的诸多因素,阻止神经元损伤的扩延,在神经功能重建时期,开放 GJ通讯促进神经元的重塑具有重要的临床意义.
作者：蒋晓江；李书林 刊期： 2003年第07期
INTRODUCTION Mortality of profuse cerebral hemorrhage is high.Objective of therapy is to reduce injury of edema and recover brain function,improve successive rate of salvage,and decrease disability incidence.Puncture and removal of cerebral hematoma and drain with urokinase under CT dirction(0.3 cm of vertebral cerebral aperture) is safe and simple,impact of which on muscle fore and movement function is investaged in this study.
作者：李康增；郑建明；郑志雄；彭友敬；张秀英；潘彬政 刊期： 2003年第07期
INTRODUCTION Recovery of normal sexual activity is the rehabilitation objective of patients with myocardial infarction.Guide to sexual activity should not be neglected for patients and their spouses.Health sexual life is necessary for improvement of quality of life and recovery to society.However,traditional culture made nurses and doctors shirk sexual education,patients and their spouses are reluctant to talk the sex to their doctors.Sex life had been neglected.Anxiety and fear for sex can be cleared by special staffs.Nurse,therefore especially circulation nurses should comprehend techniques and knowledge about health education of sex life.
作者：郭宏；姚宏利 刊期： 2003年第07期
作者： 刊期： 2003年第07期
INTRODUCTION The headache of common nature as well as headachic epilepsy and hemicrania pianheadache often affects the children.Hemicrania is the result of mental and vascular disorder,which is examined with transcranial Doppler(TCD) and electroencephalography(EEG).In this study,we analyzed the characteristics of vascular headache of children compared with adults.
作者：孟庆荣 刊期： 2003年第07期
INTRODUCTION:Shoulder- hand syndrome(SHS) also called reflective sympathetic malnutrition is a common syndrome and often seen in stroke paralysis,which early manifestation is sudden edema of hand,pain,increased skin temperature,shoulder pain.If treatment is prolonged,muscle atrophy of hand and permanent loss of range of movement might occure.Comprehensive rehabilitation treatment has a good effect on SHS.In this article,effect of block of ganglion stellatum on SHS is observed on base of comprehensive rehabilitation treatment.
作者：曾西；陈尚康；关晨霞；姜丽；王留根 刊期： 2003年第07期
INTRODUCTION The incidence,handicapping and fatality of cerebrovascular accidence (CVA) are high.Preventing complications and sequela, promoting function recovery, using remaining function adequately and regulating psychic state can promote patients self- care ability.
作者：楚平华 刊期： 2003年第07期
中国组织工程研究杂志
主管:中华人民共和国卫生部
主办：中国康复医学会,《中国组织工程研究与临床康复》杂志社
