朱巧凤
BACKGROUND:Central nerve system has the ability of re uniting of structure and function after injury that is high plasticity,which can be strengthened and consolidated through continuous studies and training.
作者:尹少华 刊期: 2003年第01期
目的:探讨应用姑息治疗对提高晚期癌症患者生活质量 (quality of life, QOL)的影响.方法:对 96例晚期癌症患者进行姑息治疗,采用 QOL观察指标对本组病例治疗前、后评分,将 QOL分为好≥ 41分;中 21~40分;差≤ 20分共 3个等级进行评估.结果:本组病例 QOL评分,治疗前≤ 40分、治疗后≥ 41分者为 71例;治疗前≤ 20分、治疗后≥ 21分者为 12例;治疗前后无效者 13例. QOL提高者占 86%,无效为 14%.结论:姑息治疗能提高晚期癌症患者的 QOL.
作者:赵勤 刊期: 2003年第01期
目的:探讨城市与农村精神分裂症患者的家庭负担及其影响因素.方法:用家庭会谈量表( FIS)对家住城市或农村的精神分裂症患者各 70例的主要照料者进行评定,以及对患者病情与一般资料进行评定.结果:城市与农村患者照料者的 FIS总平分分别是 26.03± 7.46与 25.71± 7.54,客观负担以经济负担明显,其次是娱乐与家庭日常活动的负担,两组无显著性差异.城市患者家庭负担与其病期正性相关,农村患者家庭负担与病情严重程度正性相关.结论:对精神分裂症患者进行早期有效的防治同时,给予这些特殊家庭更多的经济与社会支持是很有必要的.
作者:郭建雄;肖爱祥;王鹏;郭扬波 刊期: 2003年第01期
0 引言腭裂患者早期行腭裂修复手术,可使腭咽闭合功能有所改善或达到完全恢复,但仍存在发音障碍,需要长期的语音矫正治疗.
作者:张永红;苏健;陈秀萍 刊期: 2003年第01期
目的:探讨老年脑血管病患者瞬目反射( BR)的改变及与临床表现的关系.方法:在眶上切迹处以脉冲方波电刺激眶上神经,用表面电极同时分别在双侧眼轮匝肌记录.一侧刺激同侧所记录到的 2个波分别为 R1, R2,刺激对侧所记录到的波为 R2'.结果:正常为 11例,异常为 25例. 25例异常者中各成分异常率为 R1: 16%, R2: 52%, R2': 46%.结论:大脑半球的病变对 BR是有影响的,主要表现在晚反应成分( R2, R2')上,呈现潜伏期延长、反应波幅降低或缺如, BR晚反应成分异常与偏瘫侧别有关,与是否存在面瘫及病变的大小、病灶的多少无明显关系.
作者:董艳娟;王苏;左桂金 刊期: 2003年第01期
INTRODUCTIONDifficulty in opening mouth is one of the severe reactions,which can affect reaction patient's existence quality severely[1- 5].Now,it is thought to be helpful for preventing difficulty in opening mouth caused by radiation by early rehabilitation training.Our research results are reported as following.
作者:朱巧凤 刊期: 2003年第01期
INTRODCTIONIncidence of osteoporosis is very high in menopausal women and the senile.There weren't satisfying therapeutic method at present and exercises,diet,shinning,drugs were the main basic treatment for osteoporosis which preventive effects were better than therapeutic effects.Scientific exercises plus diet containing high calcium or suitable supplement of calcium is an effective preventive method for osteoporosis.
作者:单述刚;段献荣 刊期: 2003年第01期
AIM:To construct adenoviral vectors for luciferase driven by human telomerase reverse transcriptase(hTERT) core promoter with multimer of MYC responsive elements.METHODS:Multimer of MYC responsive elements was cloned into the upstream site of hTERT core promoter and the modified hTERT promoter and luciferase were cloned into the plasmid pDC316 to construct shuttle plasmids which cotransfected HEK 293 cells with rescue plasmid pBHGlox(delta)E1,3Cre to achieve recombinant adenoviral vectors.The cytopathic effects and PCR using primers specific for luciferase were used to identify the recombinant adenoviral vectors.RESULTS:Adenoviral vectors with luciferase driven by hTERT core promoter with none or positive and negative six copies of MYC responsive elements were constructed and amplified.The titer of the adenovirus were 3.5× 106 pfu/ml,2.5× 106 pfu/ml and 1.5× 106 pfu/ml respectively determined by plaque assay.CONCLUSION:The further research on transciriptional targeting in osteosarcoma gene therapy can be done using adenoviral vectors with luciferase driven by hTERT promoter with MYC responsive elements.
作者:杨旻;王臻;李立文;苏明权;于文彬 刊期: 2003年第01期
0 引言肺癌患者多有凝血机制异常,同时癌细胞本身能分泌促凝物质[1,2],因此肺癌并发下肢静脉血栓临床上并不少见,血栓多数发生于深静脉,引起下肢肿胀、疼痛、跛行.
作者:谢晓冬;刘永叶;刘大为;郑振东;单学健 刊期: 2003年第01期
目的:探讨高血压患者生活满意度和精神卫生状况间的关系.方法:以生活满意度调查表和SCL90为测量工具,对68例高血压患者进行对照研究和直线相关分析.结果:高血压患者生活满意度平均得分23.4,处于中等偏下水平,除居住和子女孝顺外与正常对照均有显著性差异(P<0.01).精神卫生状况除强迫和精神病性外与正常对照均有显著性差异(P<0.01).直线相关分析提示生活满意度低导致患者抑郁、焦虑、人际敏感和躯体化症状多.结论:高血压的发病与心理应激和生活满意度有关,家庭和睦、社会保障体系健全、良好的人际关系和经济状况,是减少应激和提高患者精神卫生状况的重要环节.
作者:苏景宽;王秉康;杨文清;郭克锋 刊期: 2003年第01期
0 引言从 1998-12/2001-02,我院采用高压氧( HBO)综合治疗法治疗流行性乙型脑炎患者 30例,取得良好疗效.
作者:李鲁平;李鲁静 刊期: 2003年第01期
0 引言万拉法新有效好的抗抑郁作用,其在治疗中的疗效和安全性如何 ?对此进行了万拉法新和阿米替林治疗抑郁症的开放对照观察,现将结果报道如下.
作者:陈恩民 刊期: 2003年第01期
心脏康复医学是一门发展中的科学,它的理论与实践处于起步阶段,为适应心血管医学发展的需求,要掌握心脏临床医学的发展动向,并突出本学科特点的优势,发展成为心血管医学中重要的组成部分.心脏康复的研究有着广阔的应用前途,其研究成果将丰富康复医学和心血管临床医学.
作者:张宝慧 刊期: 2003年第01期
BACKGROUND:It is considered now that early rehabilitation interventional mechanism is related to the plasticity of brain that means after injury of neural function,central nervous system has the ability of compensation and functional recombination.
作者:许艳芳;刘姝娜 刊期: 2003年第01期
针对高能聚焦超声在肿瘤治疗的应用过程中要解决的关键问题-成像、定位和聚焦及对关键问题常用的解决方法进行了简介,在进行比较的基础上选定了成像和聚焦解决方法;并在此基础上提出了一种高能聚焦超声肿瘤治疗仪的实现方案,对超声肿瘤治疗仪的关键部件治疗头部和臂部的结构结合实现功能进行了分析.分析了高能聚焦超声肿瘤治疗仪进行肿瘤治疗的过程:术前规划和手术模拟、术中定位和跟踪和术后治疗效果的评价.
作者:项林清;马培荪;陈亚珠;潘刚 刊期: 2003年第01期
BACKGROUND:The subhypothermia treatment presents the advantages of decreasing energy metabolism and consumption of lactic acid,reducing release of active amino acid and alleviating inflammatory brain injury by cerebrovascular disease protecting blood cerebral barrier and stabilize permeability of vessel.
作者:周进;王君 刊期: 2003年第01期
目的:探讨运动疗法对妊娠糖尿病血糖的影响.方法:用上肢功率计及家庭运动方案治疗孕期在 22~34周的妊娠期血糖异常者 51例,观察运动治疗前后血糖变化情况.结果:过3~9周运动疗法治疗. 41例坚持上肢功率计运动及家庭运动的孕妇.在没有使用胰岛素的情况下,空腹血糖、餐后 1 h、餐后 2 h血糖显著降低.较运动前下降 2.0~3.5 mmol/L,达到控制范围.总有效率 80%.结论:安全有效的运动疗法对部分妊娠糖尿病患者可以免除胰岛素治疗.
作者:屠霞芬;陈文华;郁嫣嫣 刊期: 2003年第01期
INTRODUCTIONBrachium potine syndrome is also called potine cerebellum lesion syndrome,is localized at facial, acoustic,trigeminal and vestibule nerve roots.In clinic,lesion in this zone is rare.We met two cases recently. Both of cases were acute onset, with hypertension history. First symptoms were dizziness, unstability of gait,facial hemianesthesia, corneal reflex dullness,poor hearing and dystaxia.Cerebral MRI showed brachium potine with long T1 and T2, signal of focus with clear margin,enhance scan showed slight or apparent reinforcement.To determine in what degree to treat them and how to use method of evidence based medicine to determine their diagnosis and best therapy,we spent less than 3 hours on searching and gaining evidences through computer of provincial medical information center.
作者:林岚;翟明 刊期: 2003年第01期
作者: 刊期: 2003年第01期
INTRODUCTIONMassage has become a manipulation of physical therapy in recent years.Massage is based on theory of zang and fu, channel and collateral of traditional Chinese medicine,instructed by pathology,anatomy and diagnosis of western medicine and combined with kinds of massage manipulation all which have make it an important method of nondrug therapy in preventing and treatment of diseases.Massage is also a measure in rehabilitation of motion function of patients with stroke[1].
作者:李晓榕;杨海玲;聂怀利 刊期: 2003年第01期