陈超
AIM:To observe the effect of the antibody of brain derived neurotrophic factor(BDNF) by cortical microinjection on hippocampal ischemic injury rats.METHODS:Preparation of local cerebral ischemic reperfusion injury model: cortical stereostaxic approach, microinjection of BDNF antibody. Applied immunohistochemical method to observe distribution of BDNF in cortex after injection of the antibody,to observe the alteration of ischemic injury between control group and BDNF antibody group.RESULT: The volume of cerebral infarction in BDNF antibody group was larger than control group.CONCLUSION: BDNF has protection function for cerebral ischemia.
作者：陈英辉；王根发；陈兴华；姚革；陈伟；周永炜 刊期： 2003年第01期
BACKGROUND:Effect of renin angiotension aldosterone system(RAS) in onset of hypertension has been clear, but the relationship between 7 kinds of pressure regulating substances and primary and renal hypertension(HP) need a further study.
作者：邹翠敏；王伟 刊期： 2003年第01期
0 引言面神经麻痹肌电图、面神经运动潜伏期和 M波波幅的变化及其临床意义是目前诊断面神经麻痹好的、客观的定量检查手段.
作者：叶爱萍 刊期： 2003年第01期
按刘海若康复医疗小组制订的康复医疗计划进行的康复医疗活动,基本达到了预期的目的,可以预料刘海若的功能恢复将是比较理想的.从这个重症复合性损伤的个案治疗中体会到:在综合医院中,康复医疗的早期介入、与临床相关学科的密切配合、强调预防性康复和主动性康复、对多种损伤的全面康复考虑和对康复医疗功能后果的全面考虑等,是制订康复计划和实施康复医疗成功的前提条件.因此,作为综合医院临床科室的康复医学科的医生,必须具有扎实的临床基础.
作者：王茂斌；高谦；李广庆 刊期： 2003年第01期
0 引言糖尿病周围神经病变的患病率很高.中枢神经及周围神经均可累及, 尤以后者为常见.患者有疼痛前列腺素 E1或痛觉异常,常影响日常工作、睡眠,称为痛性糖尿病神经病变(PDN).
作者：张曼华；李娜；栾芳 刊期： 2003年第01期
目的:探讨高血压患者生活满意度和精神卫生状况间的关系.方法:以生活满意度调查表和SCL90为测量工具,对68例高血压患者进行对照研究和直线相关分析.结果:高血压患者生活满意度平均得分23.4,处于中等偏下水平,除居住和子女孝顺外与正常对照均有显著性差异(P<0.01).精神卫生状况除强迫和精神病性外与正常对照均有显著性差异(P<0.01).直线相关分析提示生活满意度低导致患者抑郁、焦虑、人际敏感和躯体化症状多.结论:高血压的发病与心理应激和生活满意度有关,家庭和睦、社会保障体系健全、良好的人际关系和经济状况,是减少应激和提高患者精神卫生状况的重要环节.
作者：苏景宽；王秉康；杨文清；郭克锋 刊期： 2003年第01期
BACKGROUND:Reports about average life span of psychotics are different,generally 3/4 of normal people.Rongfu soldiers mental hospital of Shanxi mainly treats psychotics who were all returning soldiers in glory.Analysis to patients with long hospitalization will do good to summing up experiences and do better service to patients.
作者：武克文；杨文丽 刊期： 2003年第01期
0 引言短暂性脑缺血发作早期可用经颅多普勒 (TCD),脑电图 /彩色脑电地形图 (EEG/BEAM)进行诊断并监测脑血管血流变化情况,但二者所见对比,准确性如何,本文对此进行探讨.
作者：王顺华 刊期： 2003年第01期
0 引言甲状腺功能亢进(甲亢)的发生与日常生活密切相关,急剧的生活变更、亲人亡故、情感刺激、竞争激烈等心理、环境因素对其发生,发展及其转归,具有重要影响.
作者：罗俊敏 刊期： 2003年第01期
AIM:To explore the dynamic changes of the activity of tissue type plasminogen activator (t PA) and type 1 plasminogen activator inhibitor (PAI 1)and its clinical significance by observing the activity of t PA and PAI 1 in patients in acute and recovery phases of arteriosclerotic cerebral infarction.METHODS:Testing the activity of plasma t PA and PAI 1 of 91 patients with arteriosclerotic cerebral infarction and 80 healthy old ages by Chromgenic substrate methods and controlling them.RESULTS:The activity of t PA in acute and recovery stage of arteriosclerotic cerebral infarction patients were apparently lower than that of control and the activity of PAI 1 were higher than that of control.Volume of cerebral infarction was negatively related to the activity of t PA and positively related to the activity of PAI 1. CONCLUSION:The plasma fibrinolytic activities of the acute and recovery stage patients with arteriosclerotic cerebral infarction declined.
作者：杜小平；张乐；杨朝东；曹贵方；郑艳珍；唐健 刊期： 2003年第01期
BACKGROUND:Hypoxic and ischemic encephalopathy(HIE) is a severe complication after asphyxia of new born.It can cause death of new born and also is an important reason for children' disablement.
作者：王素香；石润海；许嘉玲；高旋旋；陈彬彬；张雪茹 刊期： 2003年第01期
目的:了解军医大学研究生的心理健康状况和人格特征.方法:采用症状自评量表 (SCL-90)、艾森克成人个性问卷 (EPQ)对 264名军医大研究生进行测试, 619名本校本科生作为对照组.结果: (1)军医大学研究生存在心理问题者占 12.12%,低于军医本科生 21.97%的阳性率.除人际关系外,各项因子高于常模( P< 0.01),但均低于对照组( P< 0.01).女生组各项分数均低于男生组,表现在强迫、恐怖和精神病性因子有明显差异; (2)阳性者症状主要表现为强迫、人际关系敏感、敌对、抑郁和偏执; (3)与阴性者比较, SCL 90筛查阳性者个性特征表现为 N分高、 P分高、 E分低( P< 0.01).不同性别研究生 E分和 N分无显著差异.结论:部分军医大研究生有心理问题,其个性特征表现为内倾、不稳定.因此,应加强对军医大研究生这一特殊群体的心理健康教育.
作者：汪涛；韩爱华；李敏 刊期： 2003年第01期
BACKGROUND:Patients with mental disease gets into recovery stage after symptoms of acute phase are alleviated, returns to society and achieves clinical recovery.But some metal problems still exist in most patients that becomes an obstruction for patients to develop speciality and self realization.
作者：毛蕴；陈莉 刊期： 2003年第01期
BACKGROUND:Matermity blues(MB) refer to short and slight emotional pain or transient state of crying and depression.Now many studies have shown that there is closed association between the occurrence of MB and psychological and social factors and obstetric factors.
作者：金萍；李芳 刊期： 2003年第01期
0 引言本文采用珠江三角洲地区丰富的温泉矿泉水疗等自然疗养因子治疗神经衰弱 60例,疗效较满意,现报告如下.
作者：何本夫；罗磊；汪金生；徐燎原；李春雨；牛若梅；陈勇伟；袁霞 刊期： 2003年第01期
0 引言经颅多普勒( TCD)借助脉冲多普勒技术和 2 MHz频率超声波,经特定颅骨透声窗,直接描记脑血管多普勒信号,以获取脑动脉血流动力学参数,进而反应脑血管功能状态.
作者：李秀珍；史洪润；张国忠；姚勇；李新民；殷宇刚；韩恩吉 刊期： 2003年第01期
BACKGROUND:Lalopathy complicated in stroke can recovery or be restored by linguistic corrective training.
作者：张永淑；王玲 刊期： 2003年第01期
CLINICAL DATASubjects:There were 764 patients in total.And 46 patients had cerebrovascular disease with secondary epilepsy,which were examined by skull CT,excluding primary epilepsy and epilepsy caused by other reasons.There were 36 males and 10 females,aged 38 to 80 years(average 59.5).
作者：周红 刊期： 2003年第01期
BACKGROUND:Muscular tension of children with cerebral paralysis enhances and motor range of joint is limited,which directly affect motor function of children.Traditional Chinese medicine affirms the cause of cerebral paralysis is because of congenital feebleness,deficiency of liver yin and kidney yin and lack of proper care after birth.Deficiency of liver yin and kidney yin leads to lack of proper care of muscles and stagnancy of qi blood,marked by spasm of muscles and disadvantage of joint movement.
作者：韩雪；尚清 刊期： 2003年第01期
目的:在氯化铝(AlCl3)所致拟痴呆动物模型基础上,探讨雌二醇对拟痴呆小鼠记忆功能保护作用及其作用机制.方法:皮下注射AlCl370mg/d共7d,实验组腹腔注射雌二醇0.3,0.6,0.9mg/kg共20d后,用跳台、避暗等实验方法测定小鼠学习记忆能力,同时测定小鼠脑内乙酰胆碱脂酶(AchE)及脑B型单胺氧化酶(MAOB)的含量.结果:AlCl3所致痴呆小鼠记忆能力明显降低,表现为避暗、跳台实验的错误次数明显增加,以及增加脑MAOB含量及脑内AchE的含量,雌二醇各剂量组能够减少小鼠电击次数(错误次数),24h重复实验,可延长跳下平台的潜伏期及进入暗箱的潜伏期,错误次数明显减少.同时降低了脑内AchE和MAOB.结论:雌二醇对AlCl3所致痴呆小鼠记忆障碍具有保护作用,能增强学习记忆能力.
作者：顾饶胜；沈楠；王艳春；吴晓东；刘微；都培双 刊期： 2003年第01期
中国组织工程研究杂志
主管:中华人民共和国卫生部
主办：中国康复医学会,《中国组织工程研究与临床康复》杂志社
