黄景仁；黄邱朝；江蔼云；翁峰；王海军；杨玉辉
目的:验证瑞美隆(米他扎品)治疗抑郁症的有效性和安全性. 方法:采用DSM-IV(296.2或296.3)抑郁症的诊断标准,共有34 例符合入组/排除标准.进行为期6周的瑞美隆每天口服1次30mg或氟西汀每天口服1次20mg的治疗.采用HAMD、CGI评定疗效. 采用TESS、体检及实验室检查评价安全性.结果:经过6周治疗,瑞美隆组和氟西汀组的有效率分别为88.24%和82.35%,治愈率分别为64.71%和41.18%,两组间有效率和治愈率差异无显著性. 瑞美隆和氟西汀组的HAMD量表总分分别由治疗前34.24±8.79分和32.47±5.43分下降至治疗后的9 .65±10.95分和9.88±6.26分,两组治疗后各周与治疗前比较差异有显著性,两组间差异无显著性. 在治疗后第7、14、28天瑞美隆组HAMD量表睡眠紊乱分的减分较氟西汀组明显.瑞美隆组的主要不良反应是眩晕/头昏、体重增加、疲乏、腹部不适、头痛.氟西汀组的主要不良反应是呕吐/恶心、体重增加、头痛.结论:瑞美隆是一种安全、有效的新型抗抑郁药物.具有抗抑郁和抗焦虑作用,且有一定改善睡眠作用.
作者：陈晓岗；谭立文；赵靖平；李乐华；陈远光 刊期： 2002年第02期
目的:探索脑肿瘤患者认知功能障碍的特点.方法:采用CLB测验对31 例左侧大脑肿瘤患者、34例右侧大脑肿瘤患者及正常对照组进行测验.结果:(1)左侧大脑脑肿瘤组四项语言-序贯能力测验成绩明显低于对照组(P<0.05),四项空间认知能力成绩无明显差别( P>0.05),病例组CLQ为正值,表明右半球信息加工能力无明显损害;(2)右侧大脑脑肿瘤组四项空间认知能力测验成绩明显低于对照组(P<0.05),四项语言-序贯能力测验成绩中系列数字、偏旁组字、类别组词与对照组间无明显差异(P>0.05),系列声音测验成绩有明显差异(P <0.05),病例组CLQ为负值,表明左半球信息加工能力基本正常.结论:CLB可以对脑肿瘤患者认知功能障碍进行量化,是一种评估左右侧大脑肿瘤患者认知功能障碍的有效方法.
作者：张银玲；皇甫恩；侯芳；魏风英；白敏芳；贺慧兰 刊期： 2002年第02期
Objectives : To explore the relationship of psychological distress and familial rearing methods in adolescents. Methods: The mental status and fami lial rearing patterns of 40 students with psychological distress and 40 health s tudents were evaluated with SCL-90 and EMBU. Results: Sign ificant difference was detected in the scores of the two groups on the SCL-90 and EMBU. Con clusion: In appropriate methods of rearing, such as lack of emotional warmth and understandi ng, severe punishment, rejection, undue protection, are important contributing f actor to psychological distress in adolescents.
作者：宫翠风；李涛；薛秀梅；刘英；张岩 刊期： 2002年第02期
The fMRI and ERPs have played important role s in understanding neura l mechanisms of human memory. Recent studies have revealed that distinct regions in medial temporal and prefrontal areas exhibit more neural activity during suc cessful than unsuccessful memory formation. The results from different studies s uggest that relational and non-relational memories are mediated by distinct sub- regions in medial temporal and prefrontal cortex and there are extensive interac tions between them in a parallel and bi-directional fashions. Emotionally arousi ng events enhance neural activity in amygdala, which in turn may modulate proces sing in other brain regions responsible for declarative memory formation.
作者：程灶火；王力 刊期： 2002年第02期
Objective: To examine the emotional states o f asthmatic children wit h different degrees of severity, as well as the effects of emotion on change of cytokines in airway. Methods: Asthmatic children were divi ded into two groups ac cording to the degrees of severity: moderate and mild. Their emotional states we re measured and results were compared. Correlation analysis was conducted betwee n scores on emotional scales and sputum levels of IL-8.Results: Total scores on anxiety and depression were higher in the moderate group than in the mild group. Negative correlation was found between levels of anxiety and IL-8 during acute exacerbation of asthmatic condition. Conclusion: Emotional distress was found to be increased with severity of asthmatic condition in children. Anxiety contribu ted to the decreased concentration of IL-8 in asthmatic children's airway.
作者：牛轶；程自立；王高华；姜毅 刊期： 2002年第02期
Objective:To evaluate social adaptation abi lity and behavior proble ms of the psychomotor epilepsy children. Methods:63 child ren with psychomotor e pilepsy and 63 normal control subjects were examined. Results: Social adaptation ability of the psychomotor epilepsy children was lower than that of the normal children(P<0.01～0.05). There was no significant difference in the total scor es on behavior problems between the two groups. Conclusions :For the benefits o f the psychomotor epilepsy children, it is essential to consider both physical a nd psychological interventions.
作者：何任；何伋 刊期： 2002年第02期
Objective: To study anxiety, depression, lif e events and coping styl e of the middle school students. Methods: SAS, SDS, Adoles cent Self-rating Life Events Checklist, and Coping Style Questionnaire were administered to 331 junior middle school students. Results: Prevalence rates for anx iety and depression we re 26.59% and 31.42% respectively. Significant correlations were found between l ife events and SAS scores. Negative coping style was positively correlated with scores on SAS and SDS. Conclusion: Reducing school work lo ad, reduced use of cri ticism and punishment, reduced dependant and negative coping style, and increase d harmonious relationship are important strategies for reducing anxiety and depr ession among middle school students.
作者：崔明；敖翔 刊期： 2002年第02期
Objective: To explore significant psychologi cal factors and their ro les in the course of illness from chronic hepatitis B to hepatocirrhosis; to exa mine the relationship between coping styles and psychosomatic symptoms in hepati tis B patients and posthepatitic cirrhosis patients. Methods: 30 chronic hepati tis B patients and 30 posthepatitic cirrhosis patients were assessed with the Me dical Coping Method Questionnaires (MCMQ), EPQ and SCL-90. Results: There were significant differences between the two groups in psychosomatic symptoms and cop ing styles, while no reliable difference was found in personality features. Post hepatitic cirrhosis patients reported more psychosomatic symptoms than hepatitis B patients. Negative coping styles, such as resignation, was found to produce significant effect. Conclusion: Negative coping style exe rts significant effect in the illness progression from chronic hepatitis B to hepatocirrhosis. Therefo re, psychological support should be provided for chronic hepatitis B patients an d posthepatitic cirrhosis patients.
作者：何金彩；金旭如 刊期： 2002年第02期
Objective: To explore the effect of K corre ction on the profile of MMPI in different mentally disordered patients.Methods: First,analyze the cor relation of the five basic scales with and without k score.Second,compare mean s of T scores of five basic scales in schizophrenia group(n=110),affective di sorder group(n=106),neurosis group (n=36)and control group(n=64).Final ly ,explore the effect of K score on T scores of the five basic scales in the thre e experimental groups and normal group. Results: The mea n of the five basic sc ales in schizophrenia group were significantly higher than those T scores withou t adding K score.In the affective disorder group Hs,Pt and Sc were significant ly altered.In theneurosis group ,Sc and Ma were significantly altered.Only Hs was significantly altered in the control group.When K was lower or higher level,T scores of thr ee experimental groups and normal group were significantly affected. When K was moderate in magnitude,only Hs,Pd and Sc were significantly changed. Conc lusion: In clinical applications, the addition of K score has positi ve values.
作者：刘建新；姜长青；张小东；张荣丽 刊期： 2002年第02期
Objective: This paper reviewed recent resear ch on memory impairments in temporal lobe epilepsy patients, including clinical features of spatial, ver bal, visual and semantic memory disorders, as well as their mechanisms and clini cal significance.
作者：俞志鹏；王文敏；王荪 刊期： 2002年第02期
目的:了解不同持续性注意测验对注意缺陷多动障碍儿童注意障碍的评定.方法 :符合DSM-Ⅳ注意缺陷多动障碍的113名男性儿童与83名正常对照儿童分别采用视觉单目标持续性注意测验、视觉连续目标持续性注意测验和听觉持续性注意测验进行对照研究.结果: 混合型儿童的视觉单目标持续性注意测验的击中率低于对照组,听觉持续注意测验的ADHD各亚型的击中率、d'值、β值均低于对照组儿童,ADHD各亚型的虚报率高于对照组.结论: ADHD各亚型儿童存在明显的听觉持续性注意能力损害.
作者：罗学荣；李雪荣 刊期： 2002年第02期
Objective: To investigate the mental health of junior middle school teachers. Methods: 270 junior middle school teachers in Ch enzhou of Hunan Provin ce were administered SCL-90. Results: Two-fifths of subjec ts reported mental sym ptoms in varying degrees. There were significant differences in mental symptoms in respect of age and region. Conclusion: The junior midd le school teachers had different psychological problems.
作者：吴小鸥；潘孝富 刊期： 2002年第02期
目的:探索中小学教师的职业压力应对策略与其人格特征的关系.方法:被试为235名中小学教师,采用自编中小学教师职业压力应对策略问卷和人格五因素问卷进行调查.结果:(1)被动型应对与人格五因素中的情绪性有显著的正相关,与宜人性有显著的负相关;主动型应对与人格五因素中的外向性有显著的正相关;自控型应对与人格五因素中的外向性、宜人性、谨慎性有显著的正相关,与情绪性有显著的负相关;(2)人格五因素中的情绪性对被动型应对具有正向预测作用,宜人性对被动型应对具有负向预测作用;人格五因素中的外向性对主动型应对具有正向预测作用;人格五因素中的情绪性对自控型应对具有负向预测作用,外向性、谨慎性和宜人性对自控型应对具有正向预测作用.结论:教师压力应对策略与教师的人格特征有关,人格各维度对不同应对策略具有不同的预测作用.
作者：申继亮；徐富明；崔艳丽 刊期： 2002年第02期
目的:探讨精神分裂症是否伴有血清微量元素锌、铜水平的异常,及其与急性期反应的关系.方法:分别采用原子吸收光谱法、散射速率比浊法测定了42 例健康对照及67 例精神分裂症患者治疗前后的血清锌、铜和结合珠蛋白(Hp)、转铁蛋白(Tf)水平.结果:精神分裂症组急性期血清Zn、Tf水平显著低于健康对照组,Cu、Hp水平显著高于健康对照组;精神分裂症组血清Zn、Cu 和Hp 、Tf水平在缓解期(治疗6周后)均恢复至与对照组相接近的水平;精神分裂症组血清Zn与Hp水平显著负相关,Cu与Hp无显著相关;未发现 BPRS评分与血清Zn、Cu或 Hp、Tf水平之间存在明显相关关系.结论:精神分裂症急性期伴有血清微量元素Zn、Cu水平的改变,这种改变可能是与急性期反应有关的非特异性状态改变.
作者：范长河；谢光荣；刘铁桥；陈凤华；朱炎 刊期： 2002年第02期
Objective:To understand mental health of el derly women. Methods:12 4 elderly females, aged from 55-81, were assessed on the SCL-90. Resu lts:The sc ores on Compulsion and Anxiety of the SCL-90 were higher for those with age abov e 65 than those below 65. The scores on Somatization, Compulsion, Interpersonal Sensitivity, Anxiety, Depression and Phobia were higher in widows than those in marriage. Conclusion:The mental health of elderly women, espe cially the widows with advancing age, required more attention from the society.
作者：杨碧漪 刊期： 2002年第02期
目的:探讨睡眠剥夺对大鼠脑组织一氧化氮(NO)及一氧化氮合酶(NOS)影响.方法:采用小平台水环境法(Flower Pot)制作大鼠睡眠剥夺模型,采用化学法和酶法观察不同时间睡眠剥夺后大鼠额叶、海马、中脑和下丘脑NO含量及NOS活性变化.结果 :与正常对照组及大平台组比较,大鼠在SD后额叶和海马的NO含量及NOS活性增高,有显著性差异(P<0.01 ～0.05),其余脑区无显著性差异(P>0.05).随着剥夺时间的延长,额叶和海马NO含量及NOS 活性增高更加明显.结论:睡眠剥夺可致NO及NOS升高,可能与其学习障碍有关,NO可能参与大鼠的睡眠调节.
作者：吴兴曲；杨来启；王晓峰；杨喜民；张宏斌；马文涛；刘光雄；张彦；王蓉蓉 刊期： 2002年第02期
Objective: To explore effects of family inco me on subjective well- being of college students. Methods: 200 college students i n Guangzhou completed the International College Survey Questionnaire. Results: 1 ) Family income was co rrelated with life satisfaction,subjective well-being and negative emotions. 2) Subjective well-being was mainly determined by positive emotions, negative emot ions and life satisfaction but not economic income. Conclusion: Family income has some effect on subjective well-being of college students .
作者：严标宾；郑雪；邱林 刊期： 2002年第02期
目的:探索睡眠剥夺的脑机制.方法:该研究采用小平台水环境法建立大鼠睡眠剥夺模型,用fos蛋白免疫组化的方法测量脑中fos蛋白的表达,分组为白天睡眠剥夺12h组、夜晚睡眠剥夺12小时组、大平台对照组和正常单独饲养组,每组4只.结果: 睡眠剥夺使f os蛋白在皮层的广泛区域表达,脑干中同异相睡眠有关的区域有较高表达,同夜晚睡眠剥夺 12小时相比,白天睡眠剥夺12小时在视交叉上核同生物节律有关的区域表达.结论:睡眠节律改变可影响脑内fos蛋白表达.
作者：宋国萍；皇甫恩；苗丹民；冯学文 刊期： 2002年第02期
Objective: To explore the relationship between temperament and parents' educational mode to provide theoretically basis for a pplying to the educational mode to suit the instructio n to the student's level. Methods: 1000 normal children aged 3-7 were measured by NY LS 300 of them, namely, the difficult temperamental, intermediate and easy temperamental ones, were chosen accordingly in proportion to 1:1:2 parental educational mode was assessed according to Yue Dongmei's research resu lts (EMBU). Results: Solicitation and understanding factors of parents with easy temperamental childr en scored much higher than those with difficult and intermediate ones(p<0.05);the influence of mot her's solicition and understanding and father's transition interference with girls was very obvious; father's attitude was also quite different towards girls or boys, that is, fathers were more satisfied with children with easy temperament and were rather reluctant to accept those with difficult temperament . Multivariate analysis also showed that father's attitude toward girls was one of the factors affecting temperament, while mother's, showed no difference. In general, parents were more concerned about, or show ed more boys with different temperamental types was not so obvious as that to girls. Co nclusion: Parents educational mode affects the formation of children's temperament.
作者：张涌静；张金梅；李玲军 刊期： 2002年第02期
Objective:To examine neuropsychological fun ctions in a group of sch izophrenic patients. Methods:The patients were assessed b y the Halstead-Reitan neuropsychological Battery (HRB). Results:Nearly 3/4 pat ients did not show any significant sign of brain damage. The performances on TPT localization、sensory memory, and speech function were poor in patients who suffered from mild brain damage. Level of brain damage was not related to duration of illness and drug do sage. However, results of the neuropsychological functioning may be affected by drugs taken by patients. Conclusion:Global impairment in neuropsychological fun ctioning was not found in most of the patients. However, mild impairment in the sensory memory and sound discrimination functions were noted.
作者：薛继芳；戴郑生 刊期： 2002年第02期
中国临床心理学杂志
主管:中华人民共和国教育部
主办：中国心理卫生协会
