慢性疾病与转化医学(英文)杂志(Chronic Diseases and Translational Medicine，简称CDTM)创刊于2015年，是国家新闻出版广电总局批准出版的正式学术刊物(ISSN:2095-882X;CN: 10-1249/R)。CDTM由中国科学技术协会主管，中华医学会主办，总编为国际知名心血管病专家胡大一教授，曾获2013年中国科技期刊影响力提升计划(D类)支持。CDTM目前为季刊，采用纸质出版联合在线预出版和开放获取(OA)多种出版模式。同时，本刊积极探索国际化的出版方向，与科爱公司(科学出版社和爱思维尔联合成立的公司)合作，进行杂志出版经营活动，包括在其平台建立网站，运用其稿件处理系统，利用爱思维尔平台进行期刊数据分析及市场推广，以期早日跻身国际化一流期刊行列。
1、文章结构
细分-编号的部分
把你的文章分成明确定义和编号的部分。部分应该是编号1.1(1.1.1 1.1.2,…),1.2,等等。(不包括抽象的部分编号)。使用这个编号也为内部交叉引用:不仅指“文本”。任何分段可以简短的标题。每个标题应该出现在它自己的单独的线。
2、介绍
国家工作的目标,并提供足够的背景,避免详细的文献调查或结果的摘要。
3、材料和方法
提供足够的细节以使工作要复制。应该表示方法已经发表的引用:只能描述相关的修改。
4、理论/计算
一个理论部分应该扩展,而不是重复,这篇文章的背景介绍中已经处理,为进一步的工作奠定基础。相比之下,计算部分代表一个实际开发的理论基础。
5、结果
结果应该清楚和简洁。
6、讨论
这应该探索工作的结果的意义,不重复。综合结果与讨论部分往往是适当的。避免广泛引用和讨论的文献发表。
7、结论
研究的主要结论可能会提出一个简短的结论部分,可独立或形式的分段讨论或结果和讨论部分。
8、附录
如果有不止一个附录,他们应该确定为A, B,等。公式和方程在附录应单独编号:情商。(.),Eq。(A)等;在随后的附录,Eq。(责任)等等。同样的表和数据:表背书;图a . 1,等等。
9、重要的标题页信息
•标题。简洁而丰富。标题中经常使用的信息检索系统。尽可能避免缩写和公式。
•作者姓名和从属关系。姓可能模棱两可的(例如,双名),请注明清楚。现在作者的联系地址(实际工作)以下的名字。表示所有关系后立即用小写字母上标字母前面的作者的名字和适当的地址。提供完整的邮寄地址的联系,包括这个国家的名字,,如果可用,每个作者的电子邮件地址。
•相应的作者。标明谁将处理信件在裁判的所有阶段和出版,出版”。确保电话和传真号码(国家和地区代码)除了提供电子邮件地址和完整的邮寄地址。联系方式必须保持最新的通讯作者。
•现在的/永久地址。如果一个作家已经从文章中描述的工作被完成了,或者当时来访,“目前地址”(或“永久地址”)可以表示为一个脚注,作者的名字。作者确实的地址必须保留为主要工作,联系地址。上标阿拉伯数字用于这样的脚注。
10、摘要
简洁的抽象是必需的。应简要说明研究的目的,主要结果和主要结论。抽象往往是分开了这篇文章,所以它必须能够独立。出于这个原因,引用应该避免,但是如果必要,然后引用作者(年代)和(s)。同时,非标准的或不常见的缩写应避免,但如果必要,他们必须定义在第一次提到抽象的本身。
11、关键字
作者将被邀请提交关键字与他们的论文。
12、缩写
定义缩写不标准在这个领域在一个脚注放在文章的第一页。这样的缩写,是不可避免的必须定义抽象的首先提到,以及脚注。确保一致性在整个文章的缩写。
13、确认
月底核对确认在一个单独的章节引用和之前的文章没有,因此,包括他们在标题页,标题或脚注。列举那些提供帮助在研究(例如,提供语言帮助,写援助或校对文章,等等)。
14、命名法和单位
遵守国际公认的规则和约定:使用国际单位制(SI)。如果其他数量,相当于SI。作者希望呈现一个术语表应该在第二页的手稿。
15、数学公式
一般现在时公式的尽可能正常文本并使用斜线(/),而不是一条水平线为小型部分条款,例如,X / Y。原则上,变量在斜体。e的力量往往更方便地用exp。数量连续方程,必须分开显示的文本(如果被显式地在文本)。
16、脚注
脚注应谨慎使用。数量连续在整篇文章中,使用上标阿拉伯数字。许多字处理构建脚注文本,可以使用此功能。应该不是这种情况,表明脚注的位置和现在的文本脚注自己单独的文章。不包括脚注引用列表中。
17、表附注
显示表中的每一个脚注上标小写字母。
影响因子：指该期刊近两年文献的平均被引用率，即该期刊前两年论文在评价当年每篇论文被引用的平均次数
被引半衰期：衡量期刊老化速度快慢的一种指标，指某一期刊论文在某年被引用的全部次数中，较新的一半被引论文刊载的时间跨度
期刊发文量：通常是指在特定时间内，一个学术期刊所发表的论文数量。计算期刊发文量是评估期刊生产力和影响力的一个重要指标，也是学者选择投稿期刊时常常考虑的因素之一。
期刊他引率：期刊被他刊引用的次数占该刊总被引次数的比例用以测度某期刊学术交流的广度、专业面的宽窄以及学科的交叉程度
总被引频次：指该期刊自创刊以来所登载的全部论文在统计当年被引用的总次数。这是一个非常客观实际的评价指标，可以显示该期刊被使用和受重视的程度，以及在科学交流中的作用和地位。
平均引文率：在给定的时间内，期刊篇均参考文献量，用以测度期刊的平均引文水平，考察期刊吸收信息的能力以及科学交流程度的高低
作者： 刊期： 2015年第01期
作者： 刊期： 2015年第01期
Objective: The aim of this study was to determine the etiology and prevalence of pediatric CAP in Beijing using a real-time polymerase chain reaction (PCR) technique.Methods: Between February 15, 2011 and January 18, 2012, 371 pediatric patients with CAP were enrolled at Beijing Children's Hospital. Sixteen respiratory viruses and two bacteria were detected from tracheal aspirate specimens using commercially available multiplex real-time reverse transcription PCR (RT-PCR) kits.Results: A single viral pathogen was detected in 35.3%of enrolled patients, multiple viruses in 11.6%, and virus/bacteria co-infection in 17.8%. In contrast, only 6.5%of patients had a single bacterial pathogen and 2.2%were infected with multiple bacteria. The etiological agent was unknown for 26.7% of patients. The most common viruses were respiratory syncytial virus (RSV) (43.9%), rhinovirus (14.8%), parainfluenza virus (9.4%), and adenovirus (8.6%). In patients under three years of age, RSV (44.6%), rhinovirus (12.8%), and Streptococcus pneumoniae (9.9%) were the most frequent pathogens. In children aged 3e7 years, S. pneumoniae (38.9%), RSV (30.6%), Haemophilus influenzae (19.4%), and adenovirus (19.4%) were most prevalent. Finally in children over seven years, RSV (47.3%), S. pneumoniae (41.9%), and rhinovirus (21.5%) infections were most frequent.Conclusions: Viral pathogens, specifically RSV, were responsible for the majority of CAP in pediatric patients. However, both S. pneumoniae and H. influenzae contributed as major causes of disease. Commercially available multiplexing real-time PCR allowed for rapid detection of the etiological agent.Copyright ? 2015, Chinese Medical Association Production. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
作者： 刊期： 2015年第02期
作者： 刊期： 2015年第01期
Tumor necrosis factor-a (TNF-a) contributes to myocardial infarction (MI) injury. Polymorphism of TNF-a gene promoter region and secretion and release of TNF-a and its transformation by a series of signaling pathways are all changed at different points of pathophysiological process in MI. Researches also investigated TNF-a antagonists and their potential therapeutic role in the setting of MI and heart failure at both molecular and clinical level. This article briefly reviews TNF-a and its mechanism as a mediator in MI. Copyright ? 2015, Chinese Medical Association Production. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
作者： 刊期： 2015年第01期
Objective: To determine the sensitivity and significance of B-cell chimerism for the detection of early engraftment, transplant rejection, and disease relapse. Methods: The dynamic monitoring of lineage-specific cell subtypes (B, T, and NK cells) was made in 20 B-cell acute lympho-blastic leukemia (B-ALL) patients following allogeneic hematopoietic stem cell transplantation (allo-HSCT). In the early period after allo-HSCT, the latest establishment of B-cell complete chimerism (CC) was observed in a majority of patients. Results: The percentage of donor cells of B-cell lineage was lower than the percent of T-cell lineage in most of the mixed chimerism (MC) patients. During graft rejection, the frequency of patients with decreasing MC of B-, T-and NK-cell lineage were 5/5, 2/5, and 2/5. When disease relapsed, five patients showed a faster decrease of the donor percent of B-cells than of T-or NK-cells. Only one patient displayed a more rapid decrease in NK-cells than in T-or B-cells. Conclusion: Monitoring of B-cell chimerism after HSCT seems to be valuable for insuring complete engraftment, anticipating graft rejection, and relapse in B-ALL patients. Copyright ? 2015, Chinese Medical Association Production. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
作者： 刊期： 2015年第01期
作者： 刊期： 2015年第01期
Objective: Soluble CD40 (sCD40) is a potential modulator for both antitumor responses and CD40-based immunotherapy;however the levels and significance of sCD40 in non-small cell lung cancer (NSCLC) patients with malignant pleural effusion are unknown. Methods: Forty-eight patients with lung cancer were treated in our institutions from January 2008 to January 2010. Peripheral blood and pleural effusion samples were collected from each subject. sCD40 levels in plasma and malignant pleural effusions supernatant were measured. The CD40L expression on CD3t T-cells was confirmed by flow cytometric direct immunofluorescence analysis. All patients were followed up after the study ended on January 1, 2010. Results: Patients with malignant pleural effusion of NSCLC had elevated circulating and pleural effusion levels of sCD40, and these elevated sCD40 levels were associated with advanced diseases and a poor prognosis. Conclusions: These findings indicate that elevated sCD40 may have a role in modulating antitumor responses and may also be a useful prognostic marker. Copyright ? 2015, Chinese Medical Association Production. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
作者： 刊期： 2015年第01期
作者： 刊期： 2015年第01期
Objective: The aim of this study was to reveal the exact changes during the occurrence of breast cancer to explore significant new and promising genes or factors related to this disease.Methods: We compared the gene expression profiles of breast cancer tissues with its uninvolved normal breast tissues as controls using the cDNA microarray analysis in seven breast cancer patients. Further, one representative gene, named IFI30, was quanti-tatively analyzed by real-time PCR to confirm the result of the cDNA microarray analysis.Results: A total of 427 genes were identified with significantly differential expression, 221 genes were up-regulated and 206 genes were down-regulated. And the result of cDNA microarray analysis was validated by detection of IFI30 mRNA level changes by real-time PCR. Genes for cell proliferation, cell cycle, cell division, mitosis, apoptosis, and immune response were enriched in the up-regulated genes, while genes for cell adhesion, proteolysis, and transport were significantly enriched in the down-regulated genes in breast cancer tissues compared with normal breast tissues by a gene ontology analysis.Conclusion: Our present study revealed a range of differentially expressed genes between breast cancer tissues and normal breast tissues, and provide candidate genes for further study focusing on the pathogenesis and new biomarkers for breast cancer.Copyright ? 2015, Chinese Medical Association Production. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
作者： 刊期： 2015年第02期
先后投了两篇文章，审稿1个多月，直接退稿！搞不明白。。。
退得挺快，挺好的[流泪]
昨天联系了慢性疾病与转化医学（英文）杂志，杂志社说我的文章还在初审当中，不知道要什么时候才出结果，好急，菩萨保佑过了，过了
退修了三四次，基本都是格式和缩减字数，可能文章比较符合期刊主题。样刊是平邮，大家一定要写好自己的详细地址，越细越好流泪
各位学友，这个期刊是不是投稿就会通过初审？ 看我很多投稿的朋友说，初审后被拒稿的也很多啊……
慢性疾病与转化医学（英文）杂志在同类刊物里面相对比较容易中，审稿有回复，退稿有温度（笔者之前的文章因改动较大，杂志建议退稿之后修改重投），不失为一种选择
文章接收速度还可以，我投稿的时间有些尴尬，恰逢是在放假的时候，耽误了一段时间。慢性疾病与转化医学（英文）杂志在学术界还是有一定地位，还是不错的。编辑老师也很不错，比较推荐大家投此杂志。
五天了还是已发回执状态 什么情况?有人知道么
慢性疾病与转化医学（英文）杂志编辑的态度非常认真、和蔼，来回修改了好几次，很快就录用了。国内的顶级杂志，影响力很大，看来我的选择还是没有错的。给你们竖个大拇指。
慢性疾病与转化医学（英文）杂志校稿认真负责，每次打电话都不厌其烦地回答我的不解之处。外审专家的审稿意见也很诚恳详细，对文章帮助很大！杂志质量还是挺不错的。
