程晋成；沈月萍；王水平；吴杨
为了解早期康复治疗对急性脑卒中患者偏瘫上肢愈后的影响,对 24例急性脑卒中患者在神经内科常规治疗基础上加早期康复治疗,观察患者上肢运动功能恢复方面的效果.结果证明早期康复治疗对脑卒中患者的上肢功能恢复有益.
作者：张辉；王毳 刊期： 2003年第07期
目的胰岛素样生长因子- 1(IGF- 1)已被证实具有神经营养和保护功能,然而对其在弥漫性脑损伤 (DBI)中的作用还知之甚少,该研究探讨 DBI后大鼠脑皮层 IGF- 1及其受体 (IGF- 1R)表达的变化及意义.方法用 Marmarou方法制作大鼠弥漫性脑损伤模型,用免疫组织化学方法观察伤后不同时间大鼠脑皮层 IGF- 1及 IGF- 1R的表达.结果致伤后皮层 IGF- 1阳性细胞数 3 d后开始增加, 7 d后达到高峰, 14 d后恢复正常水平; IGF- 1R表达在实验过程中无显著变化.结论 IGF- 1参与了 DBI的病理生理过程,可能为临床治疗重型颅脑损伤提供新的理论依据.
作者：苏军；章翔；吴景文 刊期： 2003年第07期
INTRODUCTION The headache of common nature as well as headachic epilepsy and hemicrania pianheadache often affects the children.Hemicrania is the result of mental and vascular disorder,which is examined with transcranial Doppler(TCD) and electroencephalography(EEG).In this study,we analyzed the characteristics of vascular headache of children compared with adults.
作者：孟庆荣 刊期： 2003年第07期
AIM:To observe the expression of vascular endothelial growth factor(VEGF) and Factor VIII related antigen(FVIII- R Ag) in rats brain tissue in the border zone of the hematoma,and explore the relationship between the expression of VEGF and the brain angionesis after intracerebral hmorrhage(ICH). METHODS:Rat of model of ICH was induced by injection of collagenase physiological saline into the right caudate nucleus.The immunohistochemical methods were performed by using different antisera of VEGF and FVIII- R Ag in serial sections of rats brain at 12 h,1 d,3 d and 7 d after ICH respectively.RESULTS:The amount of VEGF positive cells was markedly increased,and reached the highest at 7th day in the border zone after ICG(P< 0.01),but there were no significant difference among the mean value of A of cells at different time points (P >0.05).Compared with the controls,both the FVIII- R Ag positive endothelial cells and the A of cells were significantly different in experimental ICH goups after 1 day.CONCLUSION:The upregulated expression of VEGF might induce proliferation of endothelial cell and angiogenesis in the border zone after ICH in rats.
作者：揣兰香；张微微；戴卫平 刊期： 2003年第07期
目的研究新生大鼠缺氧缺血时脑内血红素氧化酶- 1( HO- 1)和内源性一氧化碳( CO)及环化鸟苷酸( cGMP)的变化,探讨锌原卟啉( Znpp)的治疗作用.方法 7 d SD大鼠随机分为假手术对照组,缺氧缺血组( HI)及缺氧缺血+锌原卟啉组( HI+ Znpp).利用分光光度法测定血 COHb含量和脑匀浆 HO- 1活性;放免法测定脑匀浆 cGMP水平,并观察脑病理改变.结果 HI组在 1, 4, 12 h HO- 1、 cGMP、 CO水平与对照组比明显升高( P< 0.01),在 12 h达到高峰; HI+ Znpp组 HO- 1、 cGMP、 CO水平在 1, 4, 12 h均明显低于 HI组( P< 0.01),但仍高于对照组( P< 0.01).脑组织病理检查可见 HI组呈重度缺氧缺血改变,多数神经元细胞肿胀变性;而 Znpp组神经元变性者少.结论 HI后脑内 HO- 1活性明显增高导致内源性 CO和 cGMP增高, Znpp可阻抑这一病理生理过程,减轻脑损伤.
作者：王玲；张薇；惠延平 刊期： 2003年第07期
INTRODUCTION Recovery of normal sexual activity is the rehabilitation objective of patients with myocardial infarction.Guide to sexual activity should not be neglected for patients and their spouses.Health sexual life is necessary for improvement of quality of life and recovery to society.However,traditional culture made nurses and doctors shirk sexual education,patients and their spouses are reluctant to talk the sex to their doctors.Sex life had been neglected.Anxiety and fear for sex can be cleared by special staffs.Nurse,therefore especially circulation nurses should comprehend techniques and knowledge about health education of sex life.
作者：郭宏；姚宏利 刊期： 2003年第07期
目的神经干细胞体外培养的成功是进一步研究其分化机制的基础 ,从胚胎大鼠脑室下区分离、培养、鉴定神经干细胞 (neural stem cells,NSCs),并观察其向神经元的分化情况.方法分离胚胎 SD大鼠脑室下区的组织,采用无血清原代及传代培养方法,获得具有克隆能力的细胞群;应用免疫细胞化学方法鉴定神经干细胞并检测分化后特异性成熟神经细胞抗原的表达;应用流式细胞检测技术观测神经干细胞随时间向神经元的分化情况.结果从胚胎大鼠脑室下区分离培养的细胞群具有克隆增殖能力,表达神经上皮干细胞蛋白( nestin),分化后的细胞表达神经元、星形胶质细胞和少突胶质细胞的特异性抗原;随着贴壁后分化时间的延长,表达 nestin的细胞数量从 80.5%下降到 10.9%,而神经元特异性烯醇化酶( neuron specific enolase,NSE)阳性细胞数量则从 1.1%上升到 31.6%.结论用本方法分离的细胞具有自我更新和增殖能力,并具有多分化潜能,是中枢神经系统的干细胞;随着分化时间的延长,神经干细胞数量下降,而神经元比例有明显上升.
作者：张瑞国；万琪；李力；俞英欣；曹云新 刊期： 2003年第07期
INTRODUCTION Hiccups is autonomic intermittent contraction of Diaphragm.It is thought as a kind of nerve reflex action, and can be cured spontaneously or after treatment.But refractory hiccups isn't easy to cure because of long duration, frequent onset and severe degree.
作者：邓炳海；迟振海；王桂梅；张超；李爱民 刊期： 2003年第07期
INTRODUCTION Poems dyndrom is a kind of rarely seen clinical symptomes with multiple system impairment,including polyneuropathy, swelling of organs,endocrine disorder,M protein and skin lesions.Other symptoms including anasarca,profuse sweating,hippocratic nails and low febrile.
作者：陈玮；锁海虹；赵琳；王桂荣 刊期： 2003年第07期
INTRODUCTION Knee osteoarthritis is a regenerated change of knee hyaline cartilage, complicated with bone hyperplasia,synovitis and articular capsule and muscle changes due to old age and knee joint injury, deformity and diseases etc factors.Osteoarthritis induced many clinical manifestations including knee ache,swelling and limited motion and seriously affected the quality of the patients'.
作者：徐振奇；姜贵云；刘旭东；柴叶红；李青 刊期： 2003年第07期
针刺改善脑卒中后肢体功能障碍已有大量临床报道,以灯盏花素穴位注射方法用于脑卒中肢体功能障碍的治疗,检验水针疗法改善脑卒中后肢体功能障碍的疗法优于单纯针刺的假设.
作者：李颖 刊期： 2003年第07期
BACKGROUND:Brain tissue is often thought as the most vigorous organ and is very sensitive to hypoxia.Hyperbaric oxygenation means improving blood oxygen content for decreasing the brain harm caused by stroke.Anaerobic metabolism of brain tissue decreases and aerobic metabolism increases,which cause more power and accelerate clearing of acidic product of metabolism,so provide fine material base for regeneration of neural tissue and recovery of neural function.
作者：杨晓娟；李凯；何韬 刊期： 2003年第07期
BACKGROUND:During the therapy of cencers,it is difficult to continue chemiotherapy due to frequent vomiting,especially commonly used drugs such as side effects of cisplatin.Although new pharmacy appeared in greatly relieve vomiting effect of the chemiotherapy, there were no satisfied drugs to settle this problem.
作者：王中华；陈冬波 刊期： 2003年第07期
INTRODUCTION In this study,we investigated effect of hyperbaric oxygen(HBO) on the hypertension- induced basio- cerebral hemorrhage.The affected patients often showed signs of cerebral circulation disorder,spasm of vessels,insufficiency of cerebral blood supply and intracranial hypertension.
作者：程晋成；沈月萍；王水平；吴杨 刊期： 2003年第07期
目的言语测听在助听器的选配中有决定性的作用,中国临床应用较少,通过言语测听了解耳内式助听器和耳背式助听器的使用者在言语分辨率的差别.方法采用开放法和闭合法 ,分别对耳内式、耳背式助听器使用者,进行单耳聆听条件下的言语测试.言语信号类型选用单音节词和双音节词,每耳测听单音节词和双音节词各为 20个.结果耳内式、耳背式助听器使用者的使用效果相比,在言语分辨率上无论开放式、闭合式对双音节词、单音节词的分辨率无显著性差异( P >0.05);双音节词和单音节词的分辨率比较,开放式的状态下,有显著性差异( P< 0.05);闭合式的状态下,无显著差异( P >0.05).结论在助听器的选配中言语测听的实际实施受诸多因素的影响.
作者：高建林；杨月珍；梁晨；王晓阳；吴竹梅；杨丽 刊期： 2003年第07期
INTRODUCTION Inflammatory reaction induced by cell immunology is the important mechanism of neuron injury, degenertion and progressive necrosis during ischemia- reperfusion course[1- 2].Human leucocyte antigen- II(HLA- II) is mainly expressed by presenting antigen presenting cell(APC).While HLA- DR antigen expressed mainly on the activated T cells and had a highly specificity and played an important role in immunology reaction and immunology adjustment[2].In our experiment,we explored research in CD3/CD(16+ 56) and CD3/HLA- DR by employing monocolonel antibody and immunology fluorescent labeling and FCM technology.
作者：谭峰；顾卫；黄涛；王金良；吴海科；黄彪 刊期： 2003年第07期
作者： 刊期： 2003年第07期
INTRODUCTION Before the growth and development of brain,or before or after birth, if the brain was injured by damage or injury,permanet,partial or all of the extremeties may harbor motor or positional abnormorlites. This kind of the abnormality is changed with the development of the infant.At the same time,there were different problems and priority development points at different growth stage and can be classified as infant age, school age and puberty age.
作者：王育庆；段俊峰；施凤玲 刊期： 2003年第07期
BACKGROUND:Temporomandibular disorders ( TMD) included a group of clinical symptoms and disorder of masticate muscle group and temporomandibular joint,while its causes are not clear.TMD is characterized by pain around temporomandibular joi nt,sanp,and movement disorder in mandible,Currently,it is generally accepted that multiple factors resulted in TMD,including mental and psychological,muscular and tooth factors.Comprehensive treatment rather than single treatment is suggested for TMD.
作者：黄昊红；徐文华；李佐强；韩永红 刊期： 2003年第07期
HEALTHY EDUCATION METHOD The subject is population and population guide is performed.Healthy education was given to patients every week and prevention, treatment nutrient,parmacy and notice items of DM were instructed to the patients.Through blackboard,wallpaper,prevention manual of DM, the patients were told to control blood glucose by adjusting diet.Education direction were aimed at individuals.According to conditions,educational levels,sex,age and familial status,the nurses communicated with the patients and carefully answer their questions to receive confidence,understanding and support and promote confidence of defeat diseases.
作者：孔素琴；徐秀芳 刊期： 2003年第07期
中国组织工程研究杂志
主管:中华人民共和国卫生部
主办：中国康复医学会,《中国组织工程研究与临床康复》杂志社
