王兴鹏；张锦宏；杨国瑞
目的制作一种新的猫脑损伤后持续性植物状态模型,观察其临床特征.方法将 40只猫行硬膜外水囊置放术,然后向水囊内注入无菌水直到昏迷,并对动物模型进行评估.结果手术 1个月后,有 12只猫处于植物状态,动物模型的临床表现、体征等与持续性植物状态患者相近.结论本实验制作的持续性植物状态动物模型与临床患者相似,是一种比较理想的持续性植物状态动物模型.
作者：肖华；徐如祥；李金彩 刊期： 2003年第07期
MATERIALS AND METHODS Materials 42 cases of female patients were client from hospital,with age ranging from 38 to 55 years(average 46 years).Disease course was franging from 0.5 to 6.0 years.
作者：谢珍 刊期： 2003年第07期
目的遗传性脊髓小脑共济失调 7型( SCA7)是 SCA系列中首个确定累及视网膜的疾病,该研究探讨中国 SCA7的临床特点.方法对一个表现为视力下降、辩色力异常和共济失调的 SCA7家系 23例成员( 8例患者)进行了系统的家系调查、体格检查及头颅 MR、眼底照相、视觉诱发电位、视网膜电流图等有关的辅助检查,结合国内外文献总结 SCA7临床特点.结果该家系为常染色体显性遗传,多数患者视力损害先于共济失调,存在视网膜色素变性 , 为蓝-黄色盲或蓝色盲,无夜盲,无智能减退.结论中国 SCA7患者临床表型存在多样性.
作者：韩燕；郑惠民；丁素菊；蒋建明；余龙；黄兴华；马丽杰 刊期： 2003年第07期
目的吸毒者心血管系统受毒品损害已有许多研究,为了获取更多信息,对相关指标进行统计分析.方法 19例吸毒者和 20例健康自愿者进行了 1/4全运动量 (1/4)下的心音图运动试验.同时记录心肌收缩能力和心动周期信号.把运动后第一心音( S1)幅值对安静时 S1幅值的增加倍数定义为心力变化趋势 (Cardiac Contractility Change Trend, CCCT).结果吸毒者的 CCCT(1/4)为 3.51± 2.05, 20例健康自愿对照者的 CCCT(1/4)为 7.21± 3.40, 吸毒者与健康对照组的心力变化趋势差异有非常显著性意义( P< 0.01).结论调查研究表明,这一方法适于对吸毒者的心肌收缩能力和心力储备作量化测试和评估.调查研究所得数据有利于向吸毒者和公众警示吸毒带来的严重后果.
作者：潘传中；李俐君；杨支国；刘千业；王宇虹；肖守中 刊期： 2003年第07期
AIM:To evaluate the diagnosis value of MRI for neurovascular compression (NVC) in trigeminal neuralgia(TN) and facial spasm(FS).METHODS:15 patients with TN and 2 patient with FS underwent SE T1WI and T2WI first, then 3D- TOF- SPGR sequences.RESULTS:NVC was found in all the patients, MRI findings were consistent with the surgical operative findings completely.CONCLUSION:It is considered to be of important to use MRI to find out the causes of TN and FS,especially to utilize the 3D- TOF- SPGR sequences, which may possess high sensitivity in determining NVC.
作者：公茂青；佟志勇；李喆；王运杰 刊期： 2003年第07期
BACKGROUND:Therapy with block needle knife can block pain conduction pathway and prevent vicious cycle of pain, improve blood cirvulation and enhance inflammatory.With the help of needle knife, adhesion, keloid and muscles spasmed can be cut and isolated to active equilibarium of muscles around joints.
作者：张庆君；魏斌 刊期： 2003年第07期
目的研究新生大鼠缺氧缺血时脑内血红素氧化酶- 1( HO- 1)和内源性一氧化碳( CO)及环化鸟苷酸( cGMP)的变化,探讨锌原卟啉( Znpp)的治疗作用.方法 7 d SD大鼠随机分为假手术对照组,缺氧缺血组( HI)及缺氧缺血+锌原卟啉组( HI+ Znpp).利用分光光度法测定血 COHb含量和脑匀浆 HO- 1活性;放免法测定脑匀浆 cGMP水平,并观察脑病理改变.结果 HI组在 1, 4, 12 h HO- 1、 cGMP、 CO水平与对照组比明显升高( P< 0.01),在 12 h达到高峰; HI+ Znpp组 HO- 1、 cGMP、 CO水平在 1, 4, 12 h均明显低于 HI组( P< 0.01),但仍高于对照组( P< 0.01).脑组织病理检查可见 HI组呈重度缺氧缺血改变,多数神经元细胞肿胀变性;而 Znpp组神经元变性者少.结论 HI后脑内 HO- 1活性明显增高导致内源性 CO和 cGMP增高, Znpp可阻抑这一病理生理过程,减轻脑损伤.
作者：王玲；张薇；惠延平 刊期： 2003年第07期
MATERIALS AND METHODS Materials 18 cases females in our group had mental symptoms to various degree before and after operation,with age ranging from 38 to 51 years. There were 16 cases of psychological dependence before operation and 4 cases after operation.There were 1 case of Paranoia before operation and 8 cases after operation. There were 4 cases of delirium after oparation and 1 case of other type before operation and 2 cases after operation.All the patients were excluded space occupying lesion by head CT.
作者：李秀香；邵林萍；刘广庆 刊期： 2003年第07期
AIM:Discuss the relationship of pulse pressure and left ventricular function in hypertensive patients.METHODS:We observed the relationship of the pulse pressure and the times of again occurred coronary artery diseases, left ventricular fore and after span, left ventricular back wall thickness and left ventricular ejection fraction(EF) by color Doppler ultrasound in hypertensive patients. RESULTS:The times of again occurred coronary artery diseases, the left ventricular fore and after span and left ventricular EF of each pulse pressure group were significantly difference(P< 0.05, P< 0.01). CONCLUSION:The pulse pressure may take part in the further impair of left ventricular function coronary artery diseases.Control the pulse pressure coronary artery diseases have an important meaning in decreasing the further impair of left ventricular function.
作者：杨文；王浩；刘志发 刊期： 2003年第07期
作者： 刊期： 2003年第07期
INTRODUCTION Recovery of normal sexual activity is the rehabilitation objective of patients with myocardial infarction.Guide to sexual activity should not be neglected for patients and their spouses.Health sexual life is necessary for improvement of quality of life and recovery to society.However,traditional culture made nurses and doctors shirk sexual education,patients and their spouses are reluctant to talk the sex to their doctors.Sex life had been neglected.Anxiety and fear for sex can be cleared by special staffs.Nurse,therefore especially circulation nurses should comprehend techniques and knowledge about health education of sex life.
作者：郭宏；姚宏利 刊期： 2003年第07期
INTRODUCTION Cerebral trauma is a kind of injury of skull and brain induced by out force struck.Except the direct injury of skull and cerebral tissue, secondary injury such as intercranium hematom,cerebral edema and increased intracranial pressure always occurred.Sometimes,with compliance of fracture of cervical vertebra and spinal cord,peripheral nerve injury.If synthetic rehabilitation methods were used, good effect can be detected.
作者：唐梅 刊期： 2003年第07期
BACKGROUND:To the patients with systemic lupus erythematosus(SLE) combined with leukopenia and thrombocytopenia,psychological therapy and rehabilitation nursing have some effect on rehabilitation of patients while patients are treated with pharmacotherapy such as glucocorticoid hormone and immunosuppressant.
作者：苏庆芬；陈秀梅；叶凤珍 刊期： 2003年第07期
AIM:To observe the expression of vascular endothelial growth factor(VEGF) and Factor VIII related antigen(FVIII- R Ag) in rats brain tissue in the border zone of the hematoma,and explore the relationship between the expression of VEGF and the brain angionesis after intracerebral hmorrhage(ICH). METHODS:Rat of model of ICH was induced by injection of collagenase physiological saline into the right caudate nucleus.The immunohistochemical methods were performed by using different antisera of VEGF and FVIII- R Ag in serial sections of rats brain at 12 h,1 d,3 d and 7 d after ICH respectively.RESULTS:The amount of VEGF positive cells was markedly increased,and reached the highest at 7th day in the border zone after ICG(P< 0.01),but there were no significant difference among the mean value of A of cells at different time points (P >0.05).Compared with the controls,both the FVIII- R Ag positive endothelial cells and the A of cells were significantly different in experimental ICH goups after 1 day.CONCLUSION:The upregulated expression of VEGF might induce proliferation of endothelial cell and angiogenesis in the border zone after ICH in rats.
作者：揣兰香；张微微；戴卫平 刊期： 2003年第07期
目的了解正常人颈动脉硬化患者及脑梗死患者血清同型半胱氨酸 (serum total nomocysteine,tHcy)水平及给予叶酸和维生素 B12治疗后血 tHcy含量的变化.方法脑梗死组 80例,男 71例,女 9例,年龄 63～ 80岁,平均 74岁,符合脑梗死的诊断标准,均在发病后 2周内测定 tHcy含量;颈动脉硬化组 80例,男 71例,女 9例,年龄 62～ 79岁,平均 72岁.双侧颈动脉 B超检查均存在颈动脉硬化及 (或 )粥样斑块.以上两组均除外甲状腺功能减退及肾功能减退.入选者在测定血清叶酸、维生素 B12、肌酐、血糖、血脂水平及血压和体重指数后,各组均随机分为两组,即干预治疗组及非干预治疗组,每组 40例.干预治疗组患者给予叶酸 1.25 mg,隔日 1次,维生素 B12 8 μ g, 1次 /d,口服 10个月后复查上述各项指标.结果治疗前 3组血 tHcy水平各不相同,脑梗死组为 (16± 5) μ mol/L,颈动脉硬化组为 (14± 5) μ mol/L,正常老年人组为 (12± 3) μ mol/L, 3组比较差异有显著意义.血 tHcy含量增高,叶酸水平越低.相关分析发现,血 tHcy水平与叶酸、维生素 B12呈负相关.干预治疗后,治疗组患者的血 tHcy含量均有所下降.结论不同程度的脑缺血性疾病与血 tHcy水平有一定的关系,补充营养元素有助于降低血 tHcy水平,以减少高 tHcy对血管的素性作用.
作者：黄延焱；卢晓喆；程梅芬 刊期： 2003年第07期
目的研究急性脑血管病( acute cerebrovascular disease,ACVD)患者的职业、家庭经济收入对其记忆功能的影响.方法用修订韦氏记忆量表( WMS)检测 120例 ACVD患者的记忆功能.结果 ACVD患者的 WMS各量表粗分、量表分和 MQ值明显低于对照组;工人、农民的 WMS各量表粗分、量表分和 MQ值明显低于干部和科技工作者,其异常率则明显高于干部和科技工作人员;家庭人均收入与 WMS粗分、量表分和 MQ呈明显正相关( r=0.21～ 0.51),大多数量表分、总量表分和 MQ均表现为小于或等于 500～ 799元组明显低于大于 500～ 799元组.阳性率则仅小于 300元组明显高于 800～ 1 199元组.结论 ACVD患者瞬时、短时、长时记忆均明显损害;工人、农民的 3种记忆损害均较干部、科技工作者重;家庭人均收入少于和等于 500～ 799元者各项记忆损害亦大于 500～ 799元者;干部、科技工作职业、较高家庭收入对记忆功能损害有保护作用.
作者：王琳；高唱；周红杰 刊期： 2003年第07期
INTRODUCTION Poems dyndrom is a kind of rarely seen clinical symptomes with multiple system impairment,including polyneuropathy, swelling of organs,endocrine disorder,M protein and skin lesions.Other symptoms including anasarca,profuse sweating,hippocratic nails and low febrile.
作者：陈玮；锁海虹；赵琳；王桂荣 刊期： 2003年第07期
INTRODUCTION It has been proved recently that obesity, microalbuminuria (MAU) and low- insulin resistance are independent risk factors and increase the mortality of cardiovascular diseases in type 2 diabetic patients. In order to study the relationship between microalbuminria and early larger artery lesions in type 2 diabetic patients,we analyzed the relationship between urine albumin excretory rate and arterial hemodynamic change in lower limbs.
作者：何伟民；郭树龙；林毅辉 刊期： 2003年第07期
INTRODUCTION It is reported 70%- 90% patients show dementia psychology and behavior in patients with aging dementia (AD),which are the main causes of hospitalization.Others can not understand AD patients who also can not understand the other persons affecting quality of nursing.So,to comprehend communication skills,to support them menally are very important for improvement of AD patients' quality of life.
作者：欧正红；黄丽葵；卢玉贞；孔容冰；马超 刊期： 2003年第07期
BACKGROUND:Motor obstacle of limbs directly resulted from hemiplegia after stroke seriously affect patients′ daily work and living.Conventional medicine treatment can improve the function of hemiplegic limbs at some degree, but more and more studies confirm that conventional acupuncture therapy is an effective method to improve motor function of limbs.By point stimulating channel system, acupuncture therapy can regulate qi and smooth channel system, thus regulate whole body to achieve the goal of curing hemiplegia. Acupuncture combined with hyperbaric oxygen therapy can accelerate regeneration of cerebral cells, and promote the recovery of motor function of paralyzed limbs.
作者：张志刚；孙毓 刊期： 2003年第07期
中国组织工程研究杂志
主管:中华人民共和国卫生部
主办：中国康复医学会,《中国组织工程研究与临床康复》杂志社
